ArticleMedicine2018
Primary diffuse large B-cell lymphoma in the maxilla: A case report.
Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Article
- Germinal center B-cell diffuse large B-cell lymphoma presenting as a chin mass: a case report.Annals of medicine and surgery (2012) · 2025Article
- Challenging differentiation of oral malignant lymphoma from osteomyelitis of the jawbone: A case report.Molecular and clinical oncology · 2025Article
- Uncommon presentation of diffuse large B-cell lymphoma: oral and pulmonary involvements in a young patient: a case report.Journal of medical case reports · 2024Article
- MR features of primary bone lymphoma in children.Pediatric radiology · 2023Article
- Proposal of Diagnostic Approach of Periodontal Primary Non Hodgkin Lymphoma of Bone with Flow Cytometry as an Essential Diagnostic Component.Head and neck pathology · 2022Article
- Clinical manifestations of diffuse large B-cell lymphoma that exhibits initial symptoms in the maxilla and mandible: a single-center retrospective study.BMC oral health · 2022Article
- Primary extra-nodal non-Hodgkin's lymphoma affecting mandibular bone: a case report.The Pan African medical journal · 2022Article
- Use of Liquid-based Cytology and Cell Block Combined Technique for an Accurate Diagnosis of Oral Diffuse Large B Cell Lymphoma: A Case Report.Diagnostics (Basel, Switzerland) · 2020Article
- Diffused mixed B-cell non-Hodgkin lymphoma of mandible.Journal of oral and maxillofacial pathology : JOMFP · 2020Article
- Primary lymphoma of the tibia in children: Two case reports.Medicine · 2020Article
- Primary nasal diffuse large B-cell lymphoma with synchronous pulmonary involvement: A case report.Medicine · 2019Article
- Intraosseous Non-Hodgkin Lymphoma Mimicking a Periapical Lesion.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric DentistryArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleLymphomas are the second most common non-epithelial malignant tumors in the oral and maxillofacial region. Non-Hodgkin's lymphoma (NHL) develops at extranodal sites, and cases involving the maxilla account for less than 1% of all NHLs. We describe a case of diffuse large B-cell lymphoma (DLBCL) in the maxilla, and highlight the clinical signs, symptoms, differential diagnosis, and appropriate treatment of DLBCL in the oral cavity and maxillofacial region. PATIENT CONCERNS: A 67-year-old woman was admitted to our surgical department with pain and swelling in her right upper posterior teeth for about six months. She was previously misdiagnosed with periodontal disease and had a history of tooth extraction. DIAGNOSES: Computed tomography (CT) scan revealed extensive osteolysis in the right posterior part of the maxilla with enhanced neoplasm. A solid mass was found upon incisional biopsy, and immunohistochemistry confirmed the diagnosis of DLBCL.
interventionsThe patient was treated with six courses of rituximab, cyclophosphamide, pirarubicin, vincristine, and prednisolone (R-CHOP), followed by external irradiation treatment. OUTCOMES: The treatment was well tolerated, and the patient is presently alive after two years of follow-up. LESSONS: Non-specific symptoms, such as unclear primary dental pain and unresolved periapical swelling, can make an accurate diagnosis of DLBCL difficult, which frequently lead to delayed diagnosis. A CT or cone beam computed tomography (CBCT) scan of the maxilla and immunohistochemical staining of the biopsy specimen is recommended. Combination therapy including radiotherapy and chemotherapy is the optimal treatment for NHL.
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