Evidence map›Paper›PMID 29768190›Full record

ArticlePsychiatry research2018

A Bayesian model comparison approach to test the specificity of visual integration impairment in schizophrenia or psychosis.

Tyler B Grove, Beier Yao, Savanna A Mueller, Merranda McLaughlin, Vicki L Ellingrod, Melvin G McInnis, Stephan F Taylor, Patricia J Deldin, Ivy F Tso

Abstract readComparative Study
In one paragraph

Article in Psychiatry research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Impaired Contour Object Perception in Psychosis.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026
    Article
  3. Impaired contour object perception in psychosis.medRxiv : the preprint server for health sciences · 2024
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tyler B GroveDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA. Electronic address: tylerg@umich.edu.
Beier YaoDepartment of Psychology, Michigan State University, East Lansing, MI, USA.
Savanna A MuellerDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA.
Merranda McLaughlinDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Vicki L EllingrodDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA; College of Pharmacy, University of Michigan, Ann Arbor, MI, USA.
Melvin G McInnisDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Stephan F TaylorDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA; Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Patricia J DeldinDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA; Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Ivy F TsoDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA; Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
University of Michigan · USMichigan State University · US

Funding

Institutional Career Development CoreKL2TR002241 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELLINGROD, VICKI L · 2017 to 2021
$6.9M
Michigan Institute for Clinical and Health Research (MCHR)KL2TR000434 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$1.7M
Neural mechanisms of eye gaze perception in schizophreniaK23MH108823 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TSO, IVY FEI · 2016 to 2020
$894k
NCATS NIH HHS KL2 TR000434NCATS NIH HHS KL2 TR002241NIMH NIH HHS K23 MH108823
6 · The paper itself

Abstract

Impaired visual integration is well documented in schizophrenia and related to functional outcomes. However, it is unclear if this deficit is specific to schizophrenia, or characteristic of psychosis more broadly. To address this question, this study used a Bayesian model comparison approach to examine the evidence of three grouping models of visual integration performance in 116 individuals with schizophrenia (SZ), schizoaffective disorder (SA), bipolar disorder (BD) with or without a history of prominent psychosis (BDP+ and BDP-, respectively), or no psychiatric diagnosis (healthy controls; HC). We compared: (1) Psychosis Model (psychosis, non-psychosis), where the psychosis group included SZ, SA, and BDP+, and the non-psychosis group included BDP- and HC; (2) Schizophrenia Model (SZ, non-SZ); and (3) DSM Model (SZ, SA, BD, HC). The relationship between visual integration and general cognition was also explored. The Psychosis Model showed the strongest evidence, and visual integration was associated with general cognition in participants with psychosis. The results were consistent with the Research Domain Criteria (RDoC) framework, indicating that visual integration impairment is characteristic of psychosis and not specific to SZ or DSM categories, and may share similar disease pathways with observed neurocognitive deficits in psychotic disorders.

Indexed as

AdultBayes TheoremCognitionFemaleHumansMaleMiddle AgedPhotic StimulationPsychotic DisordersSchizophreniaSchizophrenic PsychologyVision DisordersBipolar disorderNeurocognitionSchizoaffective disorderTransdiagnosticVisual processing

Identifiers

PMID29768190
PMCPMC6448399
OpenAlexW2800191725

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.