Trial reportEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2018
Direct pulp capping in primary molars using a resin-modified Portland cement-based material (TheraCal) compared to MTA with 12-month follow-up: a randomised clinical trial.
Trial report in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Efficacy of theracal as pulp capping material in permanent dentition: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Resin-Modified Calcium Silicate-Based Materials Versus Conventional Formulations in Primary Teeth: A Systematic Review and Meta-Analysis of Clinical and Radiographic Outcomes of Vital Pulp Therapy Procedures in Pediatric Dentistry.Journal of functional biomaterials · 2026Review
- Comparative Evaluation of Clinical and Radiographic Success Rates of Direct Pulp Capping in Primary Molars Using TheraCal LC, 3Mixtatin, and Nanohydroxyapatite: AnInternational journal of clinical pediatric dentistry · 2026Article
- Effect of light-cured pulp capping materials on human dental pulp cells in vitro.International endodontic journal · 2025Article
- Calcium Silicate-Based Cements in Restorative Dentistry: Vital Pulp Therapy Clinical, Radiographic, and Histological Outcomes on Deciduous and Permanent Dentition-A Systematic Review and Meta-Analysis.Materials (Basel, Switzerland) · 2024Review
- Clinical and radiographic success of TheraCal versus Formocresol in primary teeth pulpotomy: A systematic review andThe Saudi dental journal · 2024Review
- Cytotoxicity of dilutions of bioceramic materials in stem cells of human exfoliated deciduous teeth.Journal of applied oral science : revista FOB · 2024Article
- Comparative Evaluation of Effectiveness of TheraCal LC, MTA, and Calcium Hydroxide in Direct Pulp Capping in Primary Molars: Randomized Clinical Study.International journal of clinical pediatric dentistry · 2023Article
- Pulp Therapy of Primary Dentition; its Relevance despite Insufficient Histological Evidence: A Review.Iranian endodontic journal · 2023Review
- Experimental study of dexamethasone-loaded hollow hydroxyapatite microspheres applied to direct pulp capping of rat molars.Frontiers in endocrinology · 2023Article
- Clinical Efficacy of Biomimetic Bioactive Biomaterials for Dental Pulp Capping: A Systematic Review and Meta-Analysis.Biomimetics (Basel, Switzerland) · 2022Review
- Dental Pulp Stem Cells on Implant Surface: An In Vitro Study.BioMed research international · 2021Article
- Cytocompatibility and Bioactive Properties of Hydraulic Calcium Silicate-Based Cements (HCSCs) on Stem Cells from Human Exfoliated Deciduous Teeth (SHEDs): A Systematic Review of In Vitro Studies.Journal of clinical medicine · 2020Review
- Differential Gene Expression Changes in Human Primary Dental Pulp Cells Treated with Biodentine and TheraCal LC Compared to MTA.Biomedicines · 2020Article
- Mineral Trioxide Aggregate Applications in Endodontics: A Review.European journal of dentistry · 2020Article
- Time-Dependent Response of Human Deciduous Tooth-Derived Dental Pulp Cells Treated with TheraCal LC: Functional Analysis of Gene Interactions Compared to MTA.Journal of clinical medicine · 2020Article
- Direct pulp capping of primary molars using a novel fast-setting calcium silicate cement: a randomized clinical trial with 12-month follow-up.Biomaterial investigations in dentistry · 2019Article
- A Randomized Split Mouth Clinical Trial Comparing Mineral Trioxide Aggregate with a New Fast-setting Calcium Silicate Cement in Direct Pulp Capping of Primary Molars: A Preliminary Report from a Long-term Follow-up.International journal of clinical pediatric dentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThis study was to compare the success of resin-modified Portland cement-based material (TheraCal) with MTA in direct pulp capping (DPC) of primary molars.
methodsSymmetrical bilateral primary molars (92) from 46 healthy subjects aged 5-7 years were included in this split-mouth randomised clinical trial. DPC for small non-contaminated pulp exposures using either TheraCal or MTA were randomly performed in symmetrical molars. Thereafter, teeth were restored with amalgam. Clinical and radiographic evaluations were performed at 6 and 12 month follow-ups. Data were analysed using Chi square test at a significance level of 0.05.
resultsAt the final follow-up session 74 teeth were available. After 12 months, the overall success rates for MTA and TheraCal were 94.5 and 91.8%, respectively. The difference between outcomes of the two groups was not statistically significant (P > 0.05).
conclusionWithin the limitations of the current study, radiographic and clinical findings revealed that TheraCal exhibited a comparable outcome to MTA in DPC of primary molars after 12 months.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.