Evidence map›Paper›PMID 29767379›Full record

ArticleNeuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater2018

Individual cognitive change after DBS-surgery in Parkinson's disease patients using Reliable Change Index Methodology.

Thomas Foki, Daniela Hitzl, Walter Pirker, Klaus Novak, Gisela Pusswald, Johann Lehrner

Abstract read
In one paragraph

Article in Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thomas FokiDepartment of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria.
Daniela HitzlDepartment of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria.
Walter PirkerDepartment of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria.
Klaus NovakDepartment of Neurosurgery, Medical University of Vienna, Vienna, Austria.
Gisela PusswaldDepartment of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria.
Johann LehrnerDepartment of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria. johann.lehrner@meduniwien.ac.at.ORCID http://orcid.org/0000-0001-8270-9272

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-term therapy of Parkinson's disease (PD) with levodopa (L-DOPA) is associated with a high risk of developing motor fluctuations and dyskinesia. Deep brain stimulation (DBS) in PD patients of the subthalamic nucleus can improve these motor complications. Although the positive effect on motor symptoms has been proven, postoperative cognitive decline has been documented. To tackle the impact of PD-DBS on cognition, 18 DBS patients were compared to 25 best medically treated Parkinson's patients, 24 Mild Cognitive Impairment (MCI) patients and 12 healthy controls using the Neuropsychological Test Battery Vienna-long (NTBV-long) for cognitive outcome 12 months after first examination. Reliable change index methodology was used. Overall, there was cognitive change in individual patients, but the change was very heterogeneous with gains and losses. Further research is needed to identify the mechanisms that lead to improvement or deterioration of cognitive functions in individual cases.

Indexed as

Deep Brain StimulationCognitionCognitive DysfunctionHumansLevodopaNeuropsychological TestsParkinson DiseaseSubthalamic NucleusTreatment OutcomeLevodopaCognitionDeep brain stimulationNucleus subthalamicusParkinson

Identifiers

PMID29767379
PMCPMC6132487

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.