Evidence map›Paper›PMID 29767298›Full record

ReviewHNO2018

[Complications and side effects of conservative treatment of rhinological diseases].

I Küster, C Rudack, A Beule

Abstract readReview
PubMed Publisher
In one paragraph

Review in HNO, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

I KüsterKlinik für Hals‑, Nasen- und Ohrenheilkunde, Universitätsklinikum Münster, Kardinal-von-Galen-Ring 10, 48155, Münster, Deutschland. inga.kuester@ukmuenster.de.
C RudackKlinik für Hals‑, Nasen- und Ohrenheilkunde, Universitätsklinikum Münster, Kardinal-von-Galen-Ring 10, 48155, Münster, Deutschland.
A BeuleKlinik für Hals‑, Nasen- und Ohrenheilkunde, Universitätsklinikum Münster, Kardinal-von-Galen-Ring 10, 48155, Münster, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe spectrum of rhinological diseases is wide, as is that of their drug-based treatment. Only 1272 compounds coded R01 (nasal preparations) are listed in the ATC group (Anatomical Therapeutic Chemical Classification). Conservative therapy of rhinological diseases additionally includes systemic (often oral) application of corticosteroids, antibiotics and immunomodulators.

objectiveThe aim of this paper is to outline possible complications of medication (subdivided into classes of ingredients) commonly used to treat rhinological diseases in hospitals. Useful therapeutic and preventive measures will be presented. MATERIALS AND

methodsBased on the expert information in the current pharmacological drug index (ATC) for the R01 group as well as literature research in the PubMed, Cochrane Library and MEDLINE databases, medication used for the treatment of rhinological diseases was analysed in terms of side effects and their frequency.

resultsCommon side effects of intranasally applied medication are local irritations, burning, dryness and epistaxis. Orally or intravenously applied rhinological medication can affect the organs and lead to side effects such as cardiac dysrhythmia or alterations of the blood count. It is recommended that the therapeutic be selected on an individual basis and that the patient be thoroughly informed about possible side effects.

conclusionParticularly when treating children or pregnant or breastfeeding women, the indications of all nasal preparations should be checked carefully. The huge variety of rhinologicals enables an optimal individual selection on the basis of consideration of known side effects.

Indexed as

Conservative TreatmentDrug-Related Side Effects and Adverse ReactionsNose DiseasesAdrenal Cortex HormonesAnti-Bacterial AgentsChildEpistaxisFemaleHumansPregnancyAdrenal Cortex HormonesAnti-Bacterial AgentsAntibacterial agentsCorticosteroidsDrug therapyImmunomodulationPharmacologic actions

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.