ArticleAnimal nutrition (Zhongguo xu mu shou yi xue hui)2015
Towards the control of necrotic enteritis in broiler chickens with in-feed antibiotics phasing-out worldwide.
Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
82 citing papers in PubMed, 1 synthesis or guideline pooled it, 182 citations in OpenAlex.
- Withdrawal of antibiotic growth promoters from broiler diets: performance indexes and economic impact.Poultry science · 2019Pooled it
- Effects of probiotic and butyrate-based feed additives on growth performance, carcass yield and gut health of broiler chickens.Veterinary and animal science · 2026Article
- Innovative Approaches Against Planktonic and Biofilm-ProducingVeterinary sciences · 2026Review
- An engineered Escherichia coli-ClyA-NetB outer membrane vesicle delivery system modulates jejunal microbiota in broiler chickens with necrotic enteritis.Poultry science · 2026Article
- Intestinal microbiome in necrotic enteritis infection of broiler and comparison of treatment alternatives.Tropical animal health and production · 2026Article
- A pangenome-based strategy for designing a multi-epitope vaccine against non-toxin antigens of necrotic enteritis-associated Clostridium perfringens.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Toxinotyping, Antibiotic Resistance Profile, and In Vitro Bio-Control ofAntibiotics (Basel, Switzerland) · 2026Article
- Agglutination of Escherichia coli, Clostridium perfringens, and Salmonella enterica through competitive exclusion using potassium chloride with gum arabic.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Comparative Effects of Antibiotic and Antimicrobial Peptide on Growth Performance, Gut Morphology, Intestinal Lesion Score, Ileal Microbial Counts, and Immune Status in Broilers Challenged with Necrotic Enteritis.Probiotics and antimicrobial proteins · 2025Article
- Development of a Clostridium Perfringens Challenge Model in Broiler Chickens to Evaluate the Effects of Feed Additives.Pathogens (Basel, Switzerland) · 2025Article
- Effects of replacing antibiotics with probiotics and antimicrobial peptides on performance, gut health, carcass traits, meat quality, and welfare in broilers infected with Eimeria and Clostridium perfringens.Tropical animal health and production · 2025Article
- The Mechanistic Target of Rapamycin MediatesMicroorganisms · 2025Article
- Dietary supplementation of coffee pulp extract enhances growth performance and intestinal morphology in broiler chicken.Poultry science · 2025Article
- Evaluating the protective effects of the Toll-like receptor (TLR) 21 ligand, CpG ODN, against necrotic enteritis in broiler chickens.PloS one · 2025Article
- Demonstration of phage inhibitory action againstFrontiers in antibiotics · 2025Article
- Effect of extracted phycocyanin by-products as a synbiotic supplement on the production performance and intestinal morphology of broilers.Veterinary world · 2025Article
- Effects of AddingAnimals : an open access journal from MDPI · 2024Article
- Necrotic enteritis and antibiotic-free production of broiler chickens: Challenges in testing and using alternative products.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Review
- A comprehensive review of experimental models and induction protocols for avian necrotic enteritis over the past 2 decades.Frontiers in veterinary science · 2024Review
- Evaluation of the Immunoprotective Capacity of Five Vaccine Candidate Proteins against Avian Necrotic Enteritis and Impact on the Caecal Microbiota of Vaccinated Birds.Animals : an open access journal from MDPI · 2023Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Poultry production has undergone a substantial increase compared to the livestock industries since 1970. However, the industry worldwide is now facing challenges with the removal of in-feed antibiotics completely or gradually, as the once well-controlled poultry diseases have re-emerged to cause tremendous loss of production. Necrotic enteritis (NE) is one of the most important diseases which costs the industry over two billion dollars annually. In this paper, we review the progress on the etiology of NE and its control through dietary modifications, pre- and probiotics, short chain fatty acids, and vaccination. The other likely measures resulted in the most advances in the toxin characterization are also discussed. Vaccine strategies may have greater potential for the control of NE mainly due to clearer etiology of NE having been elucidated in recent years with the identification of necrotic enteritis toxin B-like (NetB) toxin. Therefore, the use of alternatives to in-feed antibiotics with a better understanding of the relationship between nutrition and NE, and limiting exposure to infectious agents through biosecurity and vaccination, might be a tool to reduce the incidence of NE and to improve gut health in the absence of in-feed antibiotics. More importantly, the combinations of different measures may achieve greater protection of birds against the disease. Among all the alternatives investigated, prebiotics, organic acids and vaccination have shown improved gastrointestinal health and thus, have potential for the control of NE.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.