Evidence map›Paper›PMID 29766641›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2019

Tailoring the homing capacity of human Tregs for directed migration to sites of Th1-inflammation or intestinal regions.

R E Hoeppli, K N MacDonald, P Leclair, V C W Fung, M Mojibian, J Gillies, S M R Rahavi, A I M Campbell, S K Gandhi, A M Pesenacker and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Article
  9. Article
  10. Tonic-signaling chimeric antigen receptors drive human regulatory T cell exhaustion.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Intestinal Regulatory T Cells.Advances in experimental medicine and biology · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

R E HoeppliDepartment of Surgery, University of British Columbia & British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.
K N MacDonaldSchool of Biomedical Engineering, University of British Columbia, Vancouver, BC, Canada.
P LeclairDepartment of Pediatrics, University of British Columbia & British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.
V C W FungDepartment of Surgery, University of British Columbia & British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.
M MojibianDepartment of Surgery, University of British Columbia & British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.
J GilliesDepartment of Surgery, University of British Columbia & British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.
S M R RahaviDepartment of Pediatrics, University of British Columbia & British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.
A I M CampbellDepartment of Surgery, University of British Columbia & British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.
S K GandhiDepartment of Surgery, University of British Columbia & British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.
A M PesenackerDepartment of Surgery, University of British Columbia & British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.
G ReidDepartment of Pediatrics, University of British Columbia & British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.
C J LimDepartment of Pediatrics, University of British Columbia & British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.
M K LevingsDepartment of Surgery, University of British Columbia & British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.

Funding

CIHR FDN-154304CIHR MOP137033CIHR MOP93793CIHR ,TFU 127880
6 · The paper itself

Abstract

Cell-based therapy with CD4

Indexed as

AnimalsCell AdhesionCell MovementCell ProliferationChemokine CXCL10Epigenesis, GeneticFemaleHumansImmune ToleranceImmunosuppression TherapyInflammationIntegrinsInterleukin-12IntestinesMaleMiceCC chemokine receptor 9Chemokine CXCL10CXCL10 protein, humanCxcl10 protein, mouseCXCR3 protein, humanCxcr3 protein, mouseintegrin alpha4beta7IntegrinsInterleukin-12Receptors, CCRReceptors, CXCR3basic (laboratory) research/sciencecellular biologycellular transplantation (non-islet)chemokines/chemokine receptorsimmune regulationimmunosuppression/immune modulationintestinal (allograft) function/dysfunctionlymphocyte biology: traffickingtolerancetranslational research/science

Identifiers

PMID29766641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.