Evidence map›Paper›PMID 29766030›Full record

ArticleMolecular therapy. Methods & clinical development2018

Cre Recombinase Mediates the Removal of Bacterial Backbone to Efficiently Generate rSV40.

Xiaoxia Shi, Matthew Ryan Ykema, Jaco Hazenoot, Lysbeth Ten Bloemendaal, Irene Mancini, Machteld Odijk, Peter de Haan, Piter J Bosma

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiaoxia ShiTytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, the Netherlands.
Matthew Ryan YkemaTytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, the Netherlands.
Jaco HazenootTytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, the Netherlands.
Lysbeth Ten BloemendaalTytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, the Netherlands.
Irene ManciniAmarna Therapeutics B.V., Leiden, the Netherlands.
Machteld OdijkAmarna Therapeutics B.V., Leiden, the Netherlands.
Peter de HaanAmarna Therapeutics B.V., Leiden, the Netherlands.
Piter J BosmaTytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, the Netherlands.
Academic Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gene therapy has been shown to be a feasible approach to treat inherited disorders

Indexed as

Cre recombinaserecombinant SV40 vector

Identifiers

PMID29766030
PMCPMC5948228
OpenAlexW2791658385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.