Evidence map›Paper›PMID 29765773›Full record

ReviewESMO open2018

Optimising the use of cetuximab in the continuum of care for patients with metastatic colorectal cancer.

Richard M Goldberg, Clara Montagut, Zev A Wainberg, Philippe Ronga, François Audhuy, Julien Taieb, Sebastian Stintzing, Salvatore Siena, Daniele Santini

Open access · goldAbstract readReview
In one paragraph

Review in ESMO open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 49 citations in OpenAlex.

  1. Trial
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  7. Personalized treatment approach for HER2-positive metastatic breast cancer.Medical oncology (Northwood, London, England) · 2024
    Review
  8. Article
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  12. KRAS: A Druggable Target in Colon Cancer Patients.International journal of molecular sciences · 2022
    Review
  13. Article
  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 5 countries.

Richard M GoldbergCancer Signature Program, West Virginia University Cancer Institute, Morgantown, West Virginia, USA.
Clara MontagutGastrointestinal Cancer, Department of Medical Oncology, Hospital del Mar-IMIM, Barcelona, Spain.
Zev A WainbergUniversity of California Los Angeles David Geffen School of Medicine, Division of Hematology/Oncology, Department of Medicine, Los Angeles, California, USA.
Philippe RongaMerck KGaA, Global Medical Affairs, Darmstadt, Germany.
François AudhuyMerck KGaA, Global Medical Affairs, Darmstadt, Germany.
Julien TaiebHôpital Européen Georges-Pompidou, APHP, Paris Descartes University, Sorbonne Paris Cité, Department of GI Oncology, Paris, France.
Sebastian StintzingUniversity Hospital, Ludwig-Maximilians-University Munich, Department of Medicine III, Munich, Germany.ORCID 0000-0002-3297-5801
Salvatore SienaUniversità degli Studi di Milano, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Department of Hematology and Oncology, Milan, Italy.
Daniele SantiniUnit of Medical Oncology, Università Campus Bio-Medico, Rome, Italy.
Merck (Germany) · DEHospital Del Mar · ESLudwig-Maximilians-Universität München · DEUniversità Campus Bio-Medico · ITUniversité Paris Cité · FRUniversity of California, Los Angeles · USUniversity of Milan · ITWest Virginia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anti-epidermal growth factor receptor (EGFR) monoclonal antibody cetuximab in combination with chemotherapy is a standard of care in the first-line treatment of

Indexed as

cetuximabcontinuum of caremetastatic colorectal cancerrasretreatment

Identifiers

PMID29765773
PMCPMC5950648
OpenAlexW2800494346

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.