Evidence map›Paper›PMID 29765659›Full record

ArticleRoyal Society open science2018

Self-assembly behaviours of peptide-drug conjugates: influence of multiple factors on aggregate morphology and potential self-assembly mechanism.

Qin Fan, Yujie Ji, Jingjing Wang, Li Wu, Weidong Li, Rui Chen, Zhipeng Chen

Open access · goldAbstract read
In one paragraph

Article in Royal Society open science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Qin FanCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, People's Republic of China.
Yujie JiCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, People's Republic of China.
Jingjing WangCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, People's Republic of China.
Li WuCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, People's Republic of China.
Weidong LiCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, People's Republic of China.
Rui ChenCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, People's Republic of China.ORCID 0000-0002-8486-9007
Zhipeng ChenCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, People's Republic of China.
Google (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptide-drug conjugates (PDCs) as self-assembly prodrugs have the unique and specific features to build one-component nanomedicines. Supramolecular structure based on PDCs could form various morphologies ranging from nanotube, nanofibre, nanobelt to hydrogel. However, the assembly process of PDCs is too complex to predict or control. Herein, we investigated the effects of extrinsic factors on assembly morphology and the possible formation of nanostructures based on PDCs. To this end, we designed a PDC consisting of hydrophobic drug (

Indexed as

nanoribbonpeptide–drug conjugatesself-assembly

Identifiers

PMID29765659
PMCPMC5936924
OpenAlexW2797832353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.