Evidence map›Paper›PMID 29765626›Full record

ArticleRoyal Society open science2018

A focused library synthesis and cytotoxicity of quinones derived from the natural product bolinaquinone.

Azadeh Ghods, Jayne Gilbert, Jennifer R Baker, Cecilia C Russell, Jennette A Sakoff, Adam McCluskey

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Royal Society open science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. 2,3-Dihydroquinazolin-4(1RSC medicinal chemistry · 2024
    Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Azadeh GhodsChemistry, The University of Newcastle, University Drive Callaghan, Newcastle, New South Wales 2308, Australia.
Jayne GilbertChemistry, The University of Newcastle, University Drive Callaghan, Newcastle, New South Wales 2308, Australia.
Jennifer R BakerChemistry, The University of Newcastle, University Drive Callaghan, Newcastle, New South Wales 2308, Australia.
Cecilia C RussellChemistry, The University of Newcastle, University Drive Callaghan, Newcastle, New South Wales 2308, Australia.
Jennette A SakoffChemistry, The University of Newcastle, University Drive Callaghan, Newcastle, New South Wales 2308, Australia.
Adam McCluskeyChemistry, The University of Newcastle, University Drive Callaghan, Newcastle, New South Wales 2308, Australia.ORCID 0000-0001-7125-863X
University of Newcastle Australia · AUCalvary Mater Newcastle Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bolinaquinone is a natural product that is a structurally complex, cytotoxic sesquiterpene quinone. A scaffold simplification and focused library approach using a microwave-assisted Suzuki coupling gave 32 bolinaquinone analogues with good-to-excellent cytotoxicity profiles. Mono-arylbenzoquinones, Library

Indexed as

bolinaquinonecytotoxicitymicrowave-assisted synthesisSuzuki coupling

Identifiers

PMID29765626
PMCPMC5936891
OpenAlexW2796312257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.