Evidence map›Paper›PMID 29765497›Full record

ArticleOxidative medicine and cellular longevity2018

Di-2-pyridylhydrazone Dithiocarbamate Butyric Acid Ester Exerted Its Proliferative Inhibition against Gastric Cell via ROS-Mediated Apoptosis and Autophagy.

Xingshuang Guo, Yun Fu, Zhuo Wang, Tingting Wang, Cuiping Li, Tengfei Huang, Fulian Gao, Changzheng Li

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xingshuang GuoDepartment of Histology and Embryology, Xinxiang Medical University, Xinxiang, Henan 453003, China.
Yun FuLaboratory of Molecular Medicine, Xinxiang Medical University, Xinxiang, Henan 453003, China.
Zhuo WangDepartment of Histology and Embryology, Xinxiang Medical University, Xinxiang, Henan 453003, China.
Tingting WangLaboratory of Molecular Medicine, Xinxiang Medical University, Xinxiang, Henan 453003, China.
Cuiping LiLaboratory of Molecular Medicine, Xinxiang Medical University, Xinxiang, Henan 453003, China.
Tengfei HuangLaboratory of Molecular Medicine, Xinxiang Medical University, Xinxiang, Henan 453003, China.
Fulian GaoDepartment of Histology and Embryology, Xinxiang Medical University, Xinxiang, Henan 453003, China.ORCID 0000-0002-6106-9015
Changzheng LiLaboratory of Molecular Medicine, Xinxiang Medical University, Xinxiang, Henan 453003, China.ORCID 0000-0002-6226-5843
Xinxiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diversified biological activities of dithiocarbamates have attracted widespread attention; improving their feature or exploring their potent action of mechanism is a hot topic in medicinal research. Herein, we presented a study on synthesis and investigation of a novel dithiocarbamate, DpdtbA (di-2-pyridylhydrazone dithiocarbamate butyric acid ester), on antitumor activity. The growth inhibition assay revealed that DpdtbA had important antitumor activity for gastric cancer (GC) cell lines (IC

Indexed as

ApoptosisAutophagyButyratesCell ProliferationHumansHydrazonesReactive Oxygen SpeciesSignal TransductionThiocarbamatesButyratesHydrazonesReactive Oxygen SpeciesThiocarbamates

Identifiers

PMID29765497
PMCPMC5889906
OpenAlexW2790077358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.