Evidence map›Paper›PMID 29765457›Full record

ArticleArchives of medical science : AMS2018

High lncRNA HULC expression is associated with poor prognosis and promotes tumor progression by regulating epithelial-mesenchymal transition in prostate cancer.

Pengyi Zheng, Huibing Li, Po Xu, Xiaohui Wang, Zhenguo Shi, Qingjiang Han, Zhijun Li

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Pengyi ZhengDepartment of Urologic Surgery, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Henan, China.
Huibing LiDepartment of Urologic Surgery, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Henan, China.
Po XuDepartment of Urologic Surgery, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Henan, China.
Xiaohui WangDepartment of Urologic Surgery, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Henan, China.
Zhenguo ShiDepartment of Urologic Surgery, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Henan, China.
Qingjiang HanDepartment of Urologic Surgery, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Henan, China.
Zhijun LiDepartment of Urologic Surgery, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Henan, China.
First Affiliated Hospital of Henan University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRecently, increasing evidence has shown that long non-coding RNAs (lncRNAs) play critical roles in tumor progression and development. However, the expression pattern and biological function of lncRNA HULC (highly upregulated in liver cancer) in prostate cancer (PCa) remain largely unclear. MATERIAL AND

methodsThe expression of lncRNA HULC in 53 paired PCa tissues and cell lines was detected by quantitative real-time polymerase chain reaction (qRT-PCR). The χ

resultsOur data showed that HULC expression was upregulated in PCa tissues and cell lines compared to adjacent non-tumor tissues and the normal prostate cell line RWPE-1 (

conclusionsOur data suggested that lncRNA HULC might play oncogenic roles in PCa progression, which provided a novel therapeutic strategy for PCa patients.

Indexed as

epithelial-mesenchymal transitionHULClong non-coding RNAprostate cancer

Identifiers

PMID29765457
PMCPMC5949918
OpenAlexW2740817754

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.