Evidence map›Paper›PMID 29765456›Full record

ArticleArchives of medical science : AMS2018

Indomethacin-induced gastric damage in rats and the protective effect of donkey milk.

Ebru Tastekin, Suleyman Ayvaz, Ufuk Usta, Nurettin Aydogdu, Ekrem Cancilar, Fulya Oz Puyan

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ebru TastekinDepartment of Pathology, Medical Faculty, Trakya University, Edirne, Turkey.
Suleyman AyvazDepartment of Pediatric Surgery, Faculty of Medicine, Trakya University, Edirne, Turkey.
Ufuk UstaDepartment of Pathology, Medical Faculty, Trakya University, Edirne, Turkey.
Nurettin AydogduDepartment of Physiology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Ekrem CancilarDepartment of Pediatric Surgery, Faculty of Medicine, Trakya University, Edirne, Turkey.
Fulya Oz PuyanDepartment of Pathology, Medical Faculty, Trakya University, Edirne, Turkey.
Trakya University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIndomethacin is an anti-inflammatory drug with clearly known side effects on gastric mucosa. New treatment and side effect prevention methods are being studied. Donkey milk, as a nutritional support, has recently come into the spotlight with its anti-oxidant features, high antibody content and low allergenic properties. In this study, we investigated donkey milk's possible protective effect against acute gastric mucosal damage by indomethacin. MATERIAL AND

methodsFour groups, each composed of 8 rats, were created. Rats in the first and third groups were fed with standard rat chow, while those in the second and fourth groups were additionally fed with 25 mg/kg of donkey milk per day via nasogastric gavage. On the 11

resultsIn the donkey milk-indomethacin group, total area of erosion and degree of linear ulceration were significantly lower than in the standard food-indomethacin group (

conclusionsDonkey milk was observed to have significant protective effects against gastric damage induced by indomethacin.

Indexed as

donkey milkgastric damageindomethacinprotective effect

Identifiers

PMID29765456
PMCPMC5949905
OpenAlexW2476923321

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.