Evidence map›Paper›PMID 29765417›Full record

ArticleStem cells international2018

Zinc Promotes Adipose-Derived Mesenchymal Stem Cell Proliferation and Differentiation towards a Neuronal Fate.

Mi-Young Moon, Hyun Jung Kim, Bo Young Choi, Min Sohn, Tae Nyoung Chung, Sang Won Suh

Open access · goldAbstract read
In one paragraph

Article in Stem cells international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 49 citations in OpenAlex.

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  17. Neurobiology of zinc and its role in neurogenesis.European journal of nutrition · 2021
    Review
  18. Review
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  20. Zinc in the Brain: Friend or Foe?International journal of molecular sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mi-Young MoonDepartment of Physiology, College of Medicine, Hallym University, Chuncheon, Republic of Korea.
Hyun Jung KimDepartment of Physiology, College of Medicine, Hallym University, Chuncheon, Republic of Korea.
Bo Young ChoiDepartment of Physiology, College of Medicine, Hallym University, Chuncheon, Republic of Korea.
Min SohnDepartment of Nursing, Inha University, Incheon, Republic of Korea.
Tae Nyoung ChungDepartment of Emergency Medicine, CHA University School of Medicine, Seongnam, Republic of Korea.ORCID 0000-0003-3537-4136
Sang Won SuhDepartment of Physiology, College of Medicine, Hallym University, Chuncheon, Republic of Korea.ORCID 0000-0002-7492-579X
Hallym University · KRCHA University · KRInha University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zinc is an essential element required for cell division, migration, and proliferation. Under zinc-deficient conditions, proliferation and differentiation of neural progenitors are significantly impaired. Adipose-derived mesenchymal stem cells (AD-MSCs) are multipotent stem cells that can differentiate into neurons. The aim of this study was to evaluate the effect of zinc on AD-MSC proliferation and differentiation. We initially examined the effect of zinc on stem cell proliferation at the undifferentiated stage. AD-MSCs showed high proliferation rates on day 6 in 30

Identifiers

PMID29765417
PMCPMC5932442
OpenAlexW2800183785

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.