Evidence map›Paper›PMID 29765284›Full record

ArticleEJIFCC2018

Influence of serum leptin levels and Q223R leptin receptor polymorphism on clinical characteristic of patients with rheumatoid arthritis from Western Mexico.

Luis I Angel-Chávez, Elizabeth Ruelas-Cinco, Jorge Hernández-Bello, Elena Castro, Mirna Vázquez-Villamar, Isela Parra-Rojas, L Michele Brennan-Bourdon, Salvador Muñoz-Barrios, Celia Guerrero-Velázquez, José Francisco Muñoz-Valle

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in EJIFCC, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Luis I Angel-ChávezInstituto de Ciencias Biomédicas, Departamento de Ciencias de la Salud, Universidad Autónoma de Ciudad Juárez, Mexico.
Elizabeth Ruelas-CincoInstituto de Investigación en Ciencias Biomédicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Mexico.
Jorge Hernández-BelloInstituto de Investigación en Ciencias Biomédicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Mexico.
Elena CastroCentro Universitario de Investigaciones Biomédicas, Universidad de Colima, Mexico.
Mirna Vázquez-VillamarUnidad Académica de Ciencias Químico-Biológicas, Universidad Autónoma de Guerrero, Mexico.
Isela Parra-RojasUnidad Académica de Ciencias Químico-Biológicas, Universidad Autónoma de Guerrero, Mexico.
L Michele Brennan-BourdonInstituto de Investigación en Ciencias Biomédicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Mexico.
Salvador Muñoz-BarriosInstituto de Investigación en Ciencias Biomédicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Mexico.
Celia Guerrero-VelázquezInstituto de Investigación en Ciencias Biomédicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Mexico.
José Francisco Muñoz-ValleInstituto de Investigación en Ciencias Biomédicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Mexico.
Universidad de Guadalajara · MXUniversidad Autónoma de Guerrero · MXUniversidad de Colima · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the present study was to evaluate the possible association between the Q223R Leptin receptor

methodsA cross-sectional study was performed with 70 RA patients and 74 controls subject (CS). Disease activity was evaluated using DAS28 score, the Q223R

resultsRA patients had significant high serum leptin levels compared with CS; leptin levels correlated strongly with body composition measures, but not with inflammatory markers, disease evolution, and activity. The genotype and allele frequencies of the Q223R

conclusionThe

Indexed as

leptinleptin receptorpolymorphismQ223Rrheumatoid arthritis

Identifiers

PMID29765284
PMCPMC5949616
OpenAlexW2985288481

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.