Evidence map›Paper›PMID 29765239›Full record

ArticleInfection and drug resistance2018

The clinical significance of silent mutations with respect to ciprofloxacin resistance in MRSA.

Chih-Cheng Lai, Chi-Chung Chen, Ying-Chen Lu, Yin-Ching Chuang, Hung-Jen Tang

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. MEFV gene variations in COVID-19 pneumonia patients (Pilot study).Journal, genetic engineering & biotechnology · 2025
    Article
  4. Article
  5. Analysis of CDR1 and MDR1 Gene Expression and ERG11 Substitutions in Clinical Candida tropicalis Isolates from Alexandria, Egypt.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  6. Discrimination of Methicillin-resistantPathogens (Basel, Switzerland) · 2022
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chih-Cheng LaiDepartment of Intensive Care Medicine, Chi Mei Medical Center, Liouying, Tainan, Taiwan.
Chi-Chung ChenDepartment of Medical Research, Chi Mei Medical Center, Tainan, Taiwan.
Ying-Chen LuDepartment of Food Science, National Chiayi University, Chiayi, Taiwan.
Yin-Ching ChuangDepartment of Medical Research, Chi Mei Medical Center, Tainan, Taiwan.
Hung-Jen TangDepartment of Health and Nutrition, Chia-Nan University of Pharmacy and Science, Tainan, Taiwan.
Chi Mei Medical Center · TWNational Chiayi University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to investigate the genotypic differences between different sequence type MRSA isolates, especially focusing on silent

methodsSeventy-nine MRSA isolates were obtained for antibiotic susceptibility tests and molecular study.

resultsAmong these isolates, we found that the MIC

conclusionMost occurrences of this

Indexed as

ciprofloxacinMRSAresistancerpoB474silent mutation

Identifiers

PMID29765239
PMCPMC5939904
OpenAlexW2801205001

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.