Evidence map›Paper›PMID 29765084›Full record

ArticleScientific reports2018

Hepatoprotective effects of Auricularia cornea var. Li. polysaccharides against the alcoholic liver diseases through different metabolic pathways.

Xiuxiu Wang, Yufei Lan, Yongfa Zhu, Shangshang Li, Min Liu, Xinling Song, Huajie Zhao, Weiru Liu, Jianjun Zhang, Shouxian Wang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 43 citations in OpenAlex.

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  13. Characterization and Hepatoprotections ofOxidative medicine and cellular longevity · 2021
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  16. Evidence-based complementary and alternative medicine : eCAM · 2020
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  17. Triterpenoids Extracted FromFrontiers in microbiology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xiuxiu WangInstitute of Plant and Environment Protection, Beijing Academy of Agriculture and Forestry Sciences, Beijing Engineering Research Center for Edible Mushroom, Key Laboratory of Urban Agriculture (North), Ministry of Agriculture, Beijing, P.R. China.
Yufei LanTaian Academy of Agricultural Sciences, Taian, 271000, P.R. China.
Yongfa ZhuCollege of Life Science, Shandong Agricultural University, Taian, 271018, P.R. China.
Shangshang LiCollege of Life Science, Shandong Agricultural University, Taian, 271018, P.R. China.
Min LiuCollege of Life Science, Shandong Agricultural University, Taian, 271018, P.R. China.
Xinling SongCollege of Life Science, Shandong Agricultural University, Taian, 271018, P.R. China.
Huajie ZhaoCollege of Life Science, Shandong Agricultural University, Taian, 271018, P.R. China.
Weiru LiuThe Second High School of Taian, Taian, 271018, P.R. China.
Jianjun ZhangCollege of Life Science, Shandong Agricultural University, Taian, 271018, P.R. China.
Shouxian WangInstitute of Plant and Environment Protection, Beijing Academy of Agriculture and Forestry Sciences, Beijing Engineering Research Center for Edible Mushroom, Key Laboratory of Urban Agriculture (North), Ministry of Agriculture, Beijing, P.R. China. wangshouxian2002@163.com.
Le JiaCollege of Life Science, Shandong Agricultural University, Taian, 271018, P.R. China. jia__le@126.com.
Shandong Agricultural University · CNNingbo Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present work was designed to evaluate the antioxidation and hepatoprotective effects of Auricularia cornea var. Li. polysaccharides (APS) and enzymatic-extractable APS (EAPS) on the acute alcohol-induced alcoholic liver diseases (ALD). The in vitro antioxidant activities demonstrated that both APS and EAPS had strong reducing power and potential effects on scavenging reactive oxygen species. The in vivo mice experiments showed that the pretreatment with APS or EAPS showed potential hepatoprotective effects on the ALD possibly by increasing the antioxidant activities, reducing the lipid peroxidation, improving the alcohol metabolism, inhibiting the expression levels of inflammatory mediators and preventing the alcohol-induced histopathological alterations. In addition, the fourier-transform infrared (FT-IR),

Indexed as

AgaricalesAnimalsAntioxidantsChromatography, GasDisease Models, AnimalFungal PolysaccharidesGlucoseLipid PeroxidationLiver Diseases, AlcoholicMaleMiceProton Magnetic Resonance SpectroscopyReactive Oxygen SpeciesSpectroscopy, Fourier Transform InfraredTreatment OutcomeXyloseAntioxidantsFungal PolysaccharidesGlucoseReactive Oxygen SpeciesXylose

Identifiers

PMID29765084
PMCPMC5953970
OpenAlexW2806436637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.