Evidence map›Paper›PMID 29765064›Full record

ArticleScientific reports2018

Non-alcoholic fatty liver disease incidence, remission and risk factors among a general Chinese population with a 6-year follow-up.

Jing Wu, Shumei He, Hongqin Xu, Xiumei Chi, Jie Sun, Xiaomei Wang, Xiuzhu Gao, Ruihong Wu, Mingbai Shao, Heng Zhao and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Jing WuDepartment of Gerontology, The First Hospital of Jilin University, Xinmin Street, Changchun, 130021, China.
Shumei HeDepartment of Gerontology, The First Hospital of Jilin University, Xinmin Street, Changchun, 130021, China.
Hongqin XuDepartment of Hepatology, The First Hospital of Jilin University, Xinmin Street, Changchun, 130021, China.
Xiumei ChiDepartment of Hepatology, The First Hospital of Jilin University, Xinmin Street, Changchun, 130021, China.
Jie SunDepartment of Gerontology, The First Hospital of Jilin University, Xinmin Street, Changchun, 130021, China.
Xiaomei WangDepartment of Hepatology, The First Hospital of Jilin University, Xinmin Street, Changchun, 130021, China.
Xiuzhu GaoDepartment of Hepatology, The First Hospital of Jilin University, Xinmin Street, Changchun, 130021, China.
Ruihong WuDepartment of Hepatology, The First Hospital of Jilin University, Xinmin Street, Changchun, 130021, China.
Mingbai ShaoDepartment of Gerontology, The First Hospital of Jilin University, Xinmin Street, Changchun, 130021, China.
Heng ZhaoDepartment of Gerontology, The First Hospital of Jilin University, Xinmin Street, Changchun, 130021, China.
Jing JiaDepartment of Abdominal ultrasound, The First Hospital of Jilin University, Xinmin Street, Changchun, 130021, China.
Chunyan WangDepartment of Gerontology, The First Hospital of Jilin University, Xinmin Street, Changchun, 130021, China. fengshe738@sohu.com.
Junqi NiuDepartment of Hepatology, The First Hospital of Jilin University, Xinmin Street, Changchun, 130021, China. junqi_niu@163.com.ORCID 0000-0002-5187-7297
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the incidence, remission and risk factors of non-alcoholic fatty liver disease (NAFLD) among a general population with a 6-year follow-up. In total, 691 individuals from the general population in Jilin, China aged 20-75 years participated in two independent cross-sectional surveys carried out in 2007 and 2013. After excluding patients with alcoholism, viral hepatitis and other liver diseases, 646 individuals were finally enrolled in our study. Of the 646 subjects, 512 did not have NAFLD at baseline, while 134 did. Of the 512 individuals without NAFLD at baseline, 188 (36.7%) developed NAFLD during the six-year follow-up period. The baseline body mass index (BMI, OR = 1.49, 1.36-1.64), high-density lipoprotein cholesterol level(HDL-C) (OR = 0.35, 0.16-0.76) and weight gain (OR = 1.22, 1.16-1.29) were independent predictors for NAFLD incidence. Of the 134 subjects with NAFLD at baseline, 33 (24.6%) had no evidence of NAFLD after 6 years. Males (OR = 4.85, 1.98-11.92) and baseline BMI levels (OR = 0.81, 0.70-0.94) were associated with NAFLD remission. Among the general population, the incidence of NAFLD mainly depended on baseline weight and weight gain. Subjects with mild baseline weights and male subjects were prone to NAFLD remission.

Indexed as

Weight GainAdultAgedBody Mass IndexChinaCholesterol, HDLCross-Sectional StudiesFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseRisk AssessmentRisk FactorsCholesterol, HDL

Identifiers

PMID29765064
PMCPMC5954048
OpenAlexW2806429151

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.