ArticleScientific reports2018
Postnatal Microstructural Developmental Trajectory of Corpus Callosum Subregions and Relationship to Clinical Factors in Very Preterm Infants.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- The intersection of neuroscience, socioeconomic status, and preterm birth.Pediatric research · 2026Review
- A rat model establishment of bronchopulmonary dysplasia-related lung & brain injury within 28 days after birth.BMC neuroscience · 2024Article
- Corpus Callosum Abnormalities at Term-Equivalent Age Are Associated with Language Development at 2 Years' Corrected Age in Infants Born Very Preterm.Journal of pediatrics. Clinical practice · 2024Article
- Corpus callosum abnormalities at term-equivalent age are associated with language development at two years corrected age in infants born very preterm.medRxiv : the preprint server for health sciences · 2023Article
- Development of an Ultrasound Scoring System to Describe Brain Maturation in Preterm Infants.AJNR. American journal of neuroradiology · 2023Article
- Automatic measurements of fetal intracranial volume from 3D ultrasound scans.Frontiers in neuroimaging · 2022Article
- Early micro- and macrostructure of sensorimotor tracts and development of cerebral palsy in high risk infants.Human brain mapping · 2021Article
- Microstructural Measures of the Inferior Longitudinal Fasciculus Predict Later Cognitive and Language Development in Infants Born With Extremely Low Birth Weight.Journal of child neurology · 2021Article
- Automating Quantitative Measures of an Established Conventional MRI Scoring System for Preterm-Born Infants Scanned between 29 and 47 Weeks' Postmenstrual Age.AJNR. American journal of neuroradiology · 2021Article
- The biometric parameters of aniso-astigmatism and its risk factor in Chinese preschool children: the Nanjing eye study.BMC ophthalmology · 2021Article
- Objectively Diagnosed Diffuse White Matter Abnormality at Term Is an Independent Predictor of Cognitive and Language Outcomes in Infants Born Very Preterm.The Journal of pediatrics · 2020Article
- Sex differences in brain connectivity and male vulnerability in very preterm children.Human brain mapping · 2020Article
- Early Detection of Cerebral Palsy Using Sensorimotor Tract Biomarkers in Very Preterm Infants.Pediatric neurology · 2019Article
- White matter microstructure and cognitive outcomes in relation to neonatal inflammation in 6-year-old children born preterm.NeuroImage. Clinical · 2019Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Our objectives were to define the microstructural developmental trajectory of six corpus callosum subregions and identify perinatal clinical factors that influence early development of these subregions in very preterm infants. We performed a longitudinal cohort study of very preterm infants (32 weeks gestational age or younger) (N = 36) who underwent structural MRI and diffusion tensor imaging serially at four time points - before 32, 32, 38, and 52 weeks postmenstrual age. We divided the corpus callosum into six subregions, performed probabilistic tractography, and used linear mixed effects models to evaluate the influence of antecedent clinical factors on its microstructural growth trajectory. The genu and splenium demonstrated the most rapid developmental maturation, exhibited by a steep increase in fractional anisotropy. We identified several factors that favored greater corpus callosum microstructural development, including advancing postmenstrual age, higher birth weight, and college level or higher maternal education. Bronchopulmonary dysplasia, low 5-minute Apgar scores, caffeine therapy/apnea of prematurity and male sex were associated with reduced corpus callosum microstructural integrity/development over the first six months after very preterm birth. We identified a unique postnatal microstructural growth trajectory and associated clinical factor profile for each of the six corpus callosum subregions that is consistent with the heterogeneous functional role of these white matter subregions.
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