Evidence map›Paper›PMID 29765024›Full record

ArticleNature communications2018

Diffusion markers of dendritic density and arborization in gray matter predict differences in intelligence.

Erhan Genç, Christoph Fraenz, Caroline Schlüter, Patrick Friedrich, Rüdiger Hossiep, Manuel C Voelkle, Josef M Ling, Onur Güntürkün, Rex E Jung

Abstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Distinct Brain Drivers and Shared Cerebello-Cortical Input in ADCY5 and SGCE Hyperkinetic Movements.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
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  5. Review
  6. Article
  7. Article
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  9. Article
  10. Article
  11. Article
  12. Article
  13. Thinking as Analogy-Making: Toward a Neural Process Account of General Intelligence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Erhan GençInstitute of Cognitive Neuroscience, Biopsychology, Department of Psychology, Ruhr University Bochum, 44801, Bochum, Germany. erhan.genc@rub.de.
Christoph FraenzInstitute of Cognitive Neuroscience, Biopsychology, Department of Psychology, Ruhr University Bochum, 44801, Bochum, Germany.
Caroline SchlüterInstitute of Cognitive Neuroscience, Biopsychology, Department of Psychology, Ruhr University Bochum, 44801, Bochum, Germany.
Patrick FriedrichInstitute of Cognitive Neuroscience, Biopsychology, Department of Psychology, Ruhr University Bochum, 44801, Bochum, Germany.
Rüdiger HossiepTeam Test Development, Department of Psychology, Ruhr University Bochum, 44801, Bochum, Germany.
Manuel C VoelklePsychological Research Methods, Department of Psychology, Humboldt University Berlin, 10099, Berlin, Germany.
Josef M LingThe Mind Research Network/Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM, 87106, USA.
Onur GüntürkünInstitute of Cognitive Neuroscience, Biopsychology, Department of Psychology, Ruhr University Bochum, 44801, Bochum, Germany.
Rex E JungDepartment of Neurosurgery, University of New Mexico, Albuquerque, NM, 87131, USA.

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
NIMH NIH HHS U54 MH091657
6 · The paper itself

Abstract

Previous research has demonstrated that individuals with higher intelligence are more likely to have larger gray matter volume in brain areas predominantly located in parieto-frontal regions. These findings were usually interpreted to mean that individuals with more cortical brain volume possess more neurons and thus exhibit more computational capacity during reasoning. In addition, neuroimaging studies have shown that intelligent individuals, despite their larger brains, tend to exhibit lower rates of brain activity during reasoning. However, the microstructural architecture underlying both observations remains unclear. By combining advanced multi-shell diffusion tensor imaging with a culture-fair matrix-reasoning test, we found that higher intelligence in healthy individuals is related to lower values of dendritic density and arborization. These results suggest that the neuronal circuitry associated with higher intelligence is organized in a sparse and efficient manner, fostering more directed information processing and less cortical activity during reasoning.

Indexed as

IntelligenceAdolescentAdultBrain MappingDendritesFemaleGray MatterHumansIntelligence TestsMaleYoung Adult

Identifiers

PMID29765024
PMCPMC5954098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.