Evidence map›Paper›PMID 29764960›Full record

ArticleG3 (Bethesda, Md.)2018

A Genomic Region Containing

Susan E Johnston, Jisca Huisman, Josephine M Pemberton

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. A comparative study on recombination activity in cattle.Genetics, selection, evolution : GSE · 2026
    Article
  3. An Increase in Male Recombination Rate With Age in Dairy Cattle Is Heritable and Polygenic.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2026
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  11. Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Susan E JohnstonInstitute of Evolutionary Biology, University of Edinburgh, Edinburgh, EH9 3FL, United Kingdom Susan.Johnston@ed.ac.uk.ORCID 0000-0002-5623-8902
Jisca HuismanInstitute of Evolutionary Biology, University of Edinburgh, Edinburgh, EH9 3FL, United Kingdom.ORCID 0000-0002-9744-7196
Josephine M PembertonInstitute of Evolutionary Biology, University of Edinburgh, Edinburgh, EH9 3FL, United Kingdom.ORCID 0000-0002-0075-1504
University of Edinburgh · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Recombination is a fundamental feature of sexual reproduction, ensuring proper disjunction, preventing mutation accumulation and generating new allelic combinations upon which selection can act. However it is also mutagenic, and breaks up favorable allelic combinations previously built up by selection. Identifying the genetic drivers of recombination rate variation is a key step in understanding the causes and consequences of this variation, how loci associated with recombination are evolving and how they affect the potential of a population to respond to selection. However, to date, few studies have examined the genetic architecture of recombination rate variation in natural populations. Here, we use pedigree data from ∼ 2,600 individuals genotyped at ∼ 38,000 SNPs to investigate the genetic architecture of individual autosomal recombination rate in a wild population of red deer (

Indexed as

GenomeGenomicsQuantitative Trait LociRecombination, GeneticAnimalsCrossing Over, GeneticDatabases, GeneticDeerFemaleGenetics, PopulationGenome-Wide Association StudyInheritance PatternsMaleMiosisMutation RateSelection, Geneticcrossovergenome-wide association studygenomic relatednessheritabilitymeiotic recombinationred deer

Identifiers

PMID29764960
PMCPMC6027875
OpenAlexW2953206664

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.