Evidence map›Paper›PMID 29764947›Full record

ReviewmBio2018

Biological Roles Played by Sphingolipids in Dimorphic and Filamentous Fungi.

Caroline Mota Fernandes, Gustavo H Goldman, Maurizio Del Poeta

Open access · goldAbstract readReview
In one paragraph

Review in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 76 citations in OpenAlex.

  1. Review
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  7. mBio · 2025
    Article
  8. Article
  9. Review
  10. A Comprehensive Analysis of the Lipidomic Signatures inJournal of fungi (Basel, Switzerland) · 2024
    Article
  11. Article
  12. Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Caroline Mota FernandesDepartment of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA.
Gustavo H GoldmanFaculdade de Ciências Farmacêuticas de Ribeirão Prêto, Universidade de São Paulo, Ribeirão Prêto, São Paulo, Brazil.ORCID 0000-0002-2986-350X
Maurizio Del PoetaDepartment of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA maurizio.delpoeta@stonybrook.edu.
Northport VA Medical Center · USStony Brook University · USUniversidade de São Paulo · BR

Funding

New antifungals targeting the synthesis of fungal sphingolipidsR01AI116420 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI Maurizio Del Poeta · 2016 to 2026
$7.6M
Lipid-mediated fungal pathogenesisR01AI125770 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI DEL POETA, MAURIZIO · 2016 to 2025
$6.2M
Role of host spingolipids against fungal infectionsI01BX002624 · VA · NORTHPORT VA MEDICAL CENTER · PI Maurizio Del Poeta · 2016 to 2026
–
BLRD VA I01 BX002624NIAID NIH HHS R01 AI116420NIAID NIH HHS R01 AI125770
6 · The paper itself

Abstract

Filamentous and dimorphic fungi cause invasive mycoses associated with high mortality rates. Among the fungal determinants involved in the establishment of infection, glycosphingolipids (GSLs) have gained increased interest in the last few decades. GSLs are ubiquitous membrane components that have been isolated from both filamentous and dimorphic species and play a crucial role in polarized growth as well as hypha-to-yeast transition. In fungi, two major classes of GSLs are found: neutral and acidic GSLs. Neutral GSLs comprise glucosylceramide and galactosylceramide, which utilize Δ4-Δ8-9-methyl-sphingadienine as a sphingoid base, linked to a C

Indexed as

Biosynthetic PathwaysFungal ProteinsFungiSphingolipidsFungal ProteinsSphingolipidsceramidedimorphic fungifatty acidsfilamentous fungifungal infectionglucosylceramidehyphalinositol phosphorylceramidesphingolipids

Identifiers

PMID29764947
PMCPMC5954224
OpenAlexW2803554384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.