Evidence map›Paper›PMID 29764939›Full record

ArticleThe Journal of biological chemistry2018

The importance of a halotyrosine dehalogenase for

Abhishek Phatarphekar, Qi Su, Suk Ho Eun, Xin Chen, Steven E Rokita

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Misregulation of bromotyrosine compromises fertility in maleProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Article
  4. Article
  5. Redox control of iodotyrosine deiodinase.Protein science : a publication of the Protein Society · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Abhishek PhatarphekarFrom the Departments of Chemistry and.
Qi SuFrom the Departments of Chemistry and.
Suk Ho EunBiology, Johns Hopkins University, Baltimore, Maryland 21218.
Xin ChenBiology, Johns Hopkins University, Baltimore, Maryland 21218.
Steven E RokitaFrom the Departments of Chemistry and rokita@jhu.edu.
Johns Hopkins University · US

Funding

The Role of a Dehalogenase in Drosophila SpermatogenesisR21AI119540 · NIAID · JOHNS HOPKINS UNIVERSITY · PI ROKITA, STEVEN E · 2015 to 2016
$428k
Howard Hughes Medical InstituteNIAID NIH HHS R21 AI119540
6 · The paper itself

Abstract

The ability of iodotyrosine deiodinase to salvage iodide from iodotyrosine has long been recognized as critical for iodide homeostasis and proper thyroid function in vertebrates. The significance of its additional ability to dehalogenate bromo- and chlorotyrosine is less apparent, and none of these functions could have been anticipated in invertebrates until recently.

Indexed as

AnimalsDrosophilaFemaleFertilityGene Expression Regulation, EnzymologicIodide PeroxidaseMaleTestisIodide PeroxidasedehalogenaseDrosophilaflavoproteinhalotyrosinereductasereproductiontyrosine

Identifiers

PMID29764939
PMCPMC6028978
OpenAlexW2803372071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.