Evidence map›Paper›PMID 29764909›Full record

ArticleHospital pediatrics2018

Ohio Pediatric Asthma Repository: Opportunities to Revise Care Practices to Decrease Time to Physiologic Readiness for Discharge.

Jeffrey M Simmons, Jocelyn M Biagini Myers, Lisa J Martin, Carolyn M Kercsmar, Christine L Schuler, Valentina V Pilipenko, John W Kroner, Hua He, Stephen R Austin, Huyen-Tran Nguyen and 6 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Hospital pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 2 countries.

Jeffrey M SimmonsDivisions of Hospital Medicine.
Jocelyn M Biagini MyersAsthma Research.
Lisa J MartinHuman Genetics, and.
Carolyn M KercsmarPulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Christine L SchulerDivisions of Hospital Medicine.
Valentina V PilipenkoHuman Genetics, and.
John W KronerAsthma Research.
Hua HeHuman Genetics, and.
Stephen R AustinAsthma Research.
Huyen-Tran NguyenAsthma Research.
Kristie R RossDepartment of Pediatrics-Pulmonary, Rainbow Babies and Children's Hospital, Cleveland, Ohio.
Karen S McCoyDivision of Pediatric Pulmonology, Nationwide Children's Hospital, Columbus, Ohio.
Sherman J AlterDepartment of Infectious Disease, Dayton Children's Hospital, Dayton, Ohio.
Samantha M GunkelmanDivision of Pediatric Hospital Medicine, Akron Children's Hospital, Akron, Ohio.
Pierre A VauthyDepartment of Pediatric Pulmonary Medicine, ProMedica Toledo Children's Hospital, Toledo, Ohio; and.
Gurjit K Khurana HersheyAsthma Research, gurjit.hershey@cchmc.org.
University of Cincinnati Medical Center · USInstitute of Human Genetics · PLAkron Children's Hospital · USCincinnati Children's Hospital Medical Center · USDayton Children's Hospital · USNationwide Children's Hospital · USProMedica Russell J. Ebeid Children's Hospital · USRainbow Babies & Children's Hospital · US

Funding

Immunology/Allergy Fellowship Training GrantT32AI060515 · NIAID · UNIVERSITY OF CINCINNATI · PI BERNSTEIN, DAVID I., ROTHENBERG, MARC E. · 2004 to 2018
$2.8M
NIAID NIH HHS T32 AI060515
6 · The paper itself

Abstract

backgroundLarge-scale, multisite studies in which researchers evaluate patient- and systems-level factors associated with pediatric asthma exacerbation outcomes are lacking. We sought to investigate patient-level risks and system-level practices related to physiologic readiness for discharge (PRD) in the prospective Ohio Pediatric Asthma Repository.

methodsParticipants were children ages 2 to 17 years admitted to an Ohio Pediatric Asthma Repository hospital for asthma exacerbation. Demographics, disease characteristics, and individual hospital practices were collected. The primary outcome was PRD timing (hours from admission or emergency department [ED] presentation until the first 4-hour albuterol spacing).

resultsData for 1005 participants were available (865 ED presentations). Several nonstandard care practices were associated with time to PRD (

conclusionsSubstantial variation in care practices for inpatient asthma treatment exists among children's hospital systems in Ohio. We found several modifiable, system-level factors and therapies that contribute to PRD that warrant further investigation to identify the best and safest care practices. We also found that there was no standardized measure of exacerbation severity used across the hospitals. The development of such a tool is a critical gap in current practice and is needed to enable definitive comparative effectiveness studies of the management of acute asthma exacerbation.

Indexed as

Emergency Service, HospitalGuideline AdherencePatient DischargeAdolescentAnti-Asthmatic AgentsAsthmaChildChild, PreschoolDexamethasoneFemaleHospitalizationHumansMaleOhioPractice Guidelines as TopicPrednisoneAnti-Asthmatic AgentsDexamethasonePrednisone

Identifiers

PMID29764909
PMCPMC8237236
OpenAlexW2806214039

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.