Evidence map›Paper›PMID 29764843›Full record

ArticleBlood advances2018

Poorly cytotoxic terminally differentiated CD56

Catherine S Forconi, Cormac P Cosgrove, Pryia Saikumar-Lakshmi, Christina E Nixon, Joslyn Foley, John Michael Ong'echa, Juliana A Otieno, Galit Alter, Christian Münz, Ann M Moormann

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Pooled it
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  16. Human natural killer cells: Form, function, and development.The Journal of allergy and clinical immunology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Catherine S ForconiDivision of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA.ORCID 0000-0001-7358-5546
Cormac P CosgroveRagon Institute of MGH, MIT and Harvard, Cambridge, MA.ORCID 0000-0001-7856-2984
Pryia Saikumar-LakshmiDivision of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA.ORCID 0000-0001-9446-5770
Christina E NixonCenter for International Health Research, Brown University, Rhode Island Hospital, Providence, RI.ORCID 0000-0003-1934-958X
Joslyn FoleyDivision of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA.
John Michael Ong'echaCenter for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
Juliana A OtienoJaramogi Oginga Odinga Teaching and Referral Hospital, Ministry of Health, Kisumu, Kenya; and.ORCID 0000-0003-2395-4707
Galit AlterRagon Institute of MGH, MIT and Harvard, Cambridge, MA.ORCID 0000-0003-1570-9445
Christian MünzViral Immunology, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.ORCID 0000-0001-6419-1940
Ann M MoormannDivision of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA.ORCID 0000-0003-1113-2829
University of Massachusetts Chan Medical School · USRagon Institute of MGH, MIT and Harvard · USBrown University · USKenya Medical Research Institute · KEMinistry of Health · KEUniversity of Zurich · CH

Funding

The role of NK cells during acute HCV infection and antiviral therapyU19AI066345 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LAUER, GEORG MICHAEL · 2005 to 2014
$8.5M
Impact of malaria on shaping immunity to EBV in the etiology of Burkitt lymphomaR01CA189806 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MOORMANN, ANN M · 2014 to 2024
$5.7M
T Cell Immunity in Endemic Burkitt LymphomaR01CA134051 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MOORMANN, ANN M · 2008 to 2012
$2.3M
NCI NIH HHS R01 CA134051NCI NIH HHS R01 CA189806NIAID NIH HHS U19 AI066345
6 · The paper itself

Abstract

Natural killer (NK) cells are critical for restricting viral infections and mediating tumor immunosurveillance. Epstein-Barr virus (EBV) and

Indexed as

Burkitt LymphomaCD56 AntigenCell DifferentiationChildChild, PreschoolHumansKenyaKiller Cells, NaturalCD56 Antigen

Identifiers

PMID29764843
PMCPMC5965049
OpenAlexW2803749704

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.