Evidence map›Paper›PMID 29764806›Full record

ArticleCancer prevention research (Philadelphia, Pa.)2018

Temporal Efficacy of a Sulforaphane-Based Broccoli Sprout Diet in Prevention of Breast Cancer through Modulation of Epigenetic Mechanisms.

Yuanyuan Li, Phillip Buckhaults, Shizhao Li, Trygve Tollefsbol

Open access · bronzeAbstract read
In one paragraph

Article in Cancer prevention research (Philadelphia, Pa.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 66 citations in OpenAlex.

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  14. The Nutriepigenome.Genes · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yuanyuan LiDepartment of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, Alabama. lyy@uab.edu.
Phillip BuckhaultsDepartment of Drug Discovery and Biomedical Sciences, University of South Carolina, Columbia, South Carolina.
Shizhao LiDepartment of Biology, University of Alabama at Birmingham, Birmingham, Alabama.
Trygve TollefsbolComprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama.
University of Alabama at Birmingham · US

Funding

Combinatorial epigenetic-based prevention of breast cancerR01CA178441 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI TOLLEFSBOL, TRYGVE O · 2014 to 2025
$3.2M
Early life prevention of breast cancer with combined epigenetic botanicalsR01CA204346 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI TOLLEFSBOL, TRYGVE O · 2017 to 2021
$1.7M
A Genetic Model for Early-Onset Breast and Colon Cancer in African AmericansU01CA158428 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI BUCKHAULTS, PHILLIP JOE, BUNZ, FRED · 2012 to 2016
$1.5M
Epigenetic mechanisms of maternal diets in human health and disease preventionK01AT009373 · NCCIH · UNIVERSITY OF MISSOURI-COLUMBIA · PI LI, YUANYUAN · 2017 to 2021
$569k
NCCIH NIH HHS K01 AT009373NCI NIH HHS R01 CA178441NCI NIH HHS R01 CA204346NCI NIH HHS U01 CA158428
6 · The paper itself

Abstract

Breast cancer is the most common cancer and the second leading cause of cancer-related death among women. An important risk factor for breast cancer is individual genetic background, which is initially generated early in human life, for example, during the processes of embryogenesis and fetal development

Indexed as

Epigenesis, GeneticAnimalsAnticarcinogenic AgentsBrassicaCarcinogenesisDisease Models, AnimalFemaleIsothiocyanatesMammary Glands, AnimalMammary Neoplasms, ExperimentalMaternal ExposureMiceMice, TransgenicPregnancyPrenatal CareSulfoxidesAnticarcinogenic AgentsIsothiocyanatessulforaphaneSulfoxides

Identifiers

PMID29764806
PMCPMC6072582
OpenAlexW2804898257

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.