Evidence map›Paper›PMID 29764793›Full record

ArticleJournal of clinical research in pediatric endocrinology2018

Evaluation of the Ovarian Reserve in Adolescents with Hashimoto’s Thyroiditis Using Serum Anti-Müllerian Hormone Levels

Ezgi Özalp Akın, Zehra Aycan

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical research in pediatric endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Ovarian reserve in adolescent girls with autoimmune thyroiditis.Archives of endocrinology and metabolism · 2023
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Anti-Müllerian Hormone and Ovarian Reserve: Update on Assessing Ovarian Function.The Journal of clinical endocrinology and metabolism · 2020
    Review
  12. Women with Autoimmune Thyroiditis have Lower Reproductive Life Span or Not? A Cross- Sectional Study.International journal of community based nursing and midwifery · 2020
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 3 countries.

Ezgi Özalp AkınUniversity of Health Sciences, Dr. Sami Ulus Children’s Health and Disease Training and Research Hospital, Clinic of Pediatrics, Ankara, TurkeyORCID 0000-0001-8055-9485
Zehra AycanUniversity of Health Sciences, Ankara Dışkapı Yıldırım Beyazıt Training and Research Hospital, Clinic of Pediatric Endocrinology, Ankara, TurkeyORCID 0000-0003-4584-2976
Ministry of Health · TROwl Research Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to evaluate ovarian reserve in adolescent girls with Hashimoto’s thyroiditis (HT) by assessment of serum anti-Müllerian hormone (AMH) levels. It was hypothesized that HT decreases ovarian reserve and AMH levels are lower in the HT group. Methods: Thirty HT patients, aged between 10-18 years, and 30 healthy girls as the control group were enrolled in this cross-sectional study. The mean serum AMH levels of the groups were compared using the Mann-Whitney U test. Results: There was no statistically significant difference between the patient and the control groups in terms of serum AMH levels. There was a negative correlation between serum AMH and thyroid stimulating hormone (TSH) levels and no correlation between serum AMH and anti-thyroid peroxidase (anti-TPO) or anti-thyroglobulin (anti-Tg) antibody levels. Conclusion: Our results show that ovarian reserve of adolescent girls, as measured by serum AMH levels, is not affected by HT. Autoimmune damage to the ovaries may take time and the adolescent period may be too early to see these effects. Follow up of the patients for reproductive abnormalities and initiation of prospective studies is recommended.

Indexed as

AdolescentAnti-Mullerian HormoneAutoantibodiesChildCross-Sectional StudiesFemaleHashimoto DiseaseHumansIodide PeroxidaseOvarian ReserveThyrotropinAnti-Mullerian Hormoneanti-thyroglobulinAutoantibodiesIodide PeroxidaseThyrotropinadolescentsanti-Müllerian hormoneHashimoto’s thyroiditisovarian reserve

Identifiers

PMID29764793
PMCPMC6280326
OpenAlexW2803850065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.