Evidence map›Paper›PMID 29763863›Full record

ArticleEnvironmental pollution (Barking, Essex : 1987)2018

Environmental tin exposure in a nationally representative sample of U.S. adults and children: The National Health and Nutrition Examination Survey 2011-2014.

Hans-Joachim Lehmler, Manuel Gadogbe, Buyun Liu, Wei Bao

Abstract read
In one paragraph

Article in Environmental pollution (Barking, Essex : 1987), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Evaluation of Fetal Exposures to Metals and Metalloids through Meconium Analyses: A Review.International journal of environmental research and public health · 2021
    Pooled it
  2. Article
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  11. Mo and Sn exposure associated with the increased of bone mineral density.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
    Article
  12. Article
  13. Article
  14. A State-of-the-Science Review on Metal Biomarkers.Current environmental health reports · 2023
    Review
  15. Bayesian inference of chemical exposures from NHANES urine biomonitoring data.Journal of exposure science & environmental epidemiology · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Levels of tin and organotin compounds in human urine samples from Iowa, United States.Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hans-Joachim LehmlerDepartment of Occupational & Environmental Health, College of Public Health, University of Iowa, Iowa City, IA, United States.
Manuel GadogbeDepartment of Occupational & Environmental Health, College of Public Health, University of Iowa, Iowa City, IA, United States.
Buyun LiuDepartment of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA, United States.
Wei BaoDepartment of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA, United States. Electronic address: wei-bao@uiowa.edu.
University of Iowa · US

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI HANS-JOACHIM LEHMLER · 1990 to 2026
$40.5M
NIEHS NIH HHS P30 ES005605
6 · The paper itself

Abstract

Tin is a naturally occurring heavy metal that occurs in the environment in both inorganic and organic forms. Human exposure to tin is almost ubiquitous; however, surprisingly little is known about factors affecting environmental tin exposure in humans. This study analyzed demographic, socioeconomic and lifestyle factors associated with total urinary tin levels in adults (N = 3522) and children (N = 1641) participating in the National Health and Nutrition Examination Survey (NHANES) 2011-2014, a nationally representative health survey in the United States. Urinary tin levels, a commonly used biomarker of environmental tin exposure, were determined by inductively coupled plasma mass spectrometry (ICP-MS). Detection frequencies of tin were 87.05% in adults and 91.29% in children. Median and geometric mean levels of urinary tin in the adult population were 0.42 μg/L and 0.49 μg/L, respectively. For children, median and geometric mean levels of urinary tin were 0.60 μg/L and 0.66 μg/L, respectively. Age was identified as an important factor associated with urinary tin levels. Median tin levels in the ≥60 year age group were almost 2-fold higher than the 20-39 year age group. Tin levels in children were 2-fold higher than in adolescents. Race/ethnicity and household income were associated with tin levels in both adults and children. In addition, physical activity was inversely associated with urinary tin levels in adults. These results demonstrate that total tin exposures vary across different segments of the general U.S. POPULATION: Because the present study does not distinguish between organic and inorganic forms of tin, further studies are needed to better characterize modifiable factors associated with exposures to specific tin compounds, with the goal of reducing the overall exposure of the U.S. POPULATION:

Indexed as

Health SurveysNutrition SurveysAdolescentAdultBiomarkersChildDemographyEnvironmental ExposureEthnicityFemaleHumansMaleMiddle AgedTinUnited StatesYoung AdultBiomarkersTinHuman exposureUrinary tinU.S. population

Identifiers

PMID29763863
PMCPMC6082152
OpenAlexW2801856905

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.