Evidence map›Paper›PMID 29763576›Full record

ArticleBrain research2018

G

Jennifer Strand, Crystal Stinson, Larry L Bellinger, Yuan Peng, Phillip R Kramer

Abstract read
In one paragraph

Article in Brain research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. VGLUT2 Is a Determinant of Dopamine Neuron Resilience in a Rotenone Model of Dopamine Neurodegeneration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jennifer StrandDepartment of Psychology, University of Texas at Arlington, Arlington, TX 76019, United States.
Crystal StinsonTexas A&M University College of Dentistry, Dallas, TX 75246, United States.
Larry L BellingerTexas A&M University College of Dentistry, Dallas, TX 75246, United States.
Yuan PengDepartment of Psychology, University of Texas at Arlington, Arlington, TX 76019, United States.
Phillip R KramerTexas A&M University College of Dentistry, Dallas, TX 75246, United States. Electronic address: pkramer@tamhsc.edu.
Texas A&M University · USThe University of Texas at Arlington · US

Funding

Estradiol and Zoster Associated Orofacial PainR01DE026749 · NIDCR · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI KRAMER, PHILLIP R · 2018 to 2022
$2.0M
Estrogen and TMJ PainR01DE022129 · NIDCR · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI KRAMER, PHILLIP R · 2012 to 2015
$1.6M
NIDCR NIH HHS R01 DE022129NIDCR NIH HHS R01 DE026749
6 · The paper itself

Abstract

Orofacial pain includes neuronal pathways that project from the trigeminal nucleus to and through the thalamus. What role the ventroposterior thalamic complex (VP) has on orofacial pain transmission is not understood. To begin to address this question an inhibitory G protein (Gi) designer receptor exclusively activated by a designer drug (DREADD) was transfected in cells of the VP using adeno-associated virus isotype 8. Virus infected cells were identified by a fluorescent tag and immunostaining. Cells were silenced after injecting the designer drug clozapine-n-oxide, which binds the designer receptor activating G

Indexed as

AnimalsG Protein-Coupled Inwardly-Rectifying Potassium ChannelsGTP-Binding Protein alpha Subunits, Gi-GoGTP-Binding ProteinsMaleNeuronsRats, Sprague-DawleySynapsinsThalamusG Protein-Coupled Inwardly-Rectifying Potassium ChannelsGTP-Binding Protein alpha Subunits, Gi-GoGTP-Binding ProteinsSynapsinsGABAGlutamateNeuronsOrofacialPainVentral posterior medial thalamus

Identifiers

PMID29763576
PMCPMC6026072
OpenAlexW2802543836

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.