ArticleAmerican journal of epidemiology2018
Association of Maternal Exposure to Childhood Abuse With Elevated Risk for Attention Deficit Hyperactivity Disorder in Offspring.
Article in American journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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The trial behind it
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- All in the Family? A Systematic Review and Meta-analysis of Parenting and Family Environment as Risk Factors for Attention-Deficit/Hyperactivity Disorder (ADHD) in Children.Prevention science : the official journal of the Society for Prevention Research · 2024Pooled it
- Mediators and moderators in the relationship between maternal childhood adversity and children's emotional and behavioural development: a systematic review and meta-analysis.Psychological medicine · 2022Pooled it
- Associations between women's childhood maltreatment and thyroid function before and during pregnancy.Scientific reports · 2026Article
- Child Autism Spectrum Disorder Following Maternal Abuse and Trauma History.Journal of autism and developmental disorders · 2026Article
- Association of maternal and paternal adverse childhood experiences with emotional and behavioral problems among preschool children.European child & adolescent psychiatry · 2025Article
- Estimating the associations between women's maltreatment in childhood and inflammatory biomarker levels prior to and during pregnancy.PloS one · 2025Article
- Thriving Beyond Adversity: A Prospective Longitudinal Cohort Study Using a Strength-Based Approach Depicts Indigenous Adolescents with Less Adverse Childhood Experiences (ACEs) Had Fewer Neurodevelopmental Disorders (NDDs).Behavioral sciences (Basel, Switzerland) · 2024Article
- Patterns of maternal adverse childhood experiences and the intergenerational association of preschool children's emotional and behavioral problems.Frontiers in psychiatry · 2024Article
- Examining implications of the developmental timing of maternal trauma for prenatal and newborn outcomes.Infant behavior & development · 2023Article
- Intergenerational transmission of the effects of maternal exposure to childhood maltreatment in the USA: a retrospective cohort study.The Lancet. Public health · 2023Article
- Association of maternal polygenic risk scores for mental illness with perinatal risk factors for offspring mental illness.Science advances · 2022Article
- Grandmothers' endocrine disruption during pregnancy, low birth weight, and preterm birth in third generation.International journal of epidemiology · 2022Article
- Maternal childhood trauma and perinatal distress are related to infants' focused attention from 6 to 18 months.Scientific reports · 2021Article
- Polygenic risk for autism, attention-deficit hyperactivity disorder, schizophrenia, major depressive disorder, and neuroticism is associated with the experience of childhood abuse.Molecular psychiatry · 2021Article
- Association between Maternal Adverse Childhood Experiences and Attention-Deficit/Hyperactivity Disorder in the Offspring: The Mediating Role of Antepartum Health Risks.Soa--ch'ongsonyon chongsin uihak = Journal of child & adolescent psychiatry · 2021Article
- Childhood maltreatment is associated with changes in mitochondrial bioenergetics in maternal, but not in neonatal immune cells.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Use of Negative Control Exposure Analysis to Evaluate Confounding: An Example of Acetaminophen Exposure and Attention-Deficit/Hyperactivity Disorder in Nurses' Health Study II.American journal of epidemiology · 2019Article
- On the Developmental Timing of Stress: Delineating Sex-Specific Effects of Stress across Development on Adult Behavior.Brain sciences · 2018Review
- Maternal Experiences of Trauma and Toddler Multisensory Attention Skills in a South African Community Cohort.Infancy : the official journal of the International Society on Infant StudiesArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Children whose mothers experienced childhood abuse are more likely to suffer various neurodevelopmental deficits. Whether an association exists specifically for attention deficit hyperactivity disorder (ADHD) is unknown. We examined the association of maternal experience of childhood abuse with ADHD in offspring, assessed by maternal report of diagnosis and validated with the ADHD Rating Scale-IV in a subsample, in the Nurses' Health Study II (n = 49,497 mothers; n = 7,607 case offspring; n = 102,151 control offspring). We examined whether 10 adverse perinatal circumstances (e.g., prematurity, smoking) or socioeconomic factors accounted for a possible association. Exposure to abuse was associated with greater prevalence of ADHD in offspring (8.7% of offspring of women exposed to severe abuse vs. 5.5% of offspring of women not abused, P = 0.0001) and with greater risk for ADHD when the model was adjusted for demographic factors (male offspring, risk ratio (RR) = 1.6, 95% confidence interval (CI): 1.3, 1.9; female offspring, RR = 2.3, 95% CI: 1.7, 3.0). After adjustment for perinatal factors, the association of maternal childhood abuse with ADHD in offspring was slightly attenuated (male offspring, RR = 1.5, 95% CI: 1.2, 1.8; female offspring, RR = 2.1, 95% CI: 1.6, 2.8). We identified an association between maternal experience of childhood abuse and risk for ADHD in offspring, which was not explained by several important perinatal risk factors or socioeconomic status.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.