Evidence map›Paper›PMID 29762545›Full record

ReviewMarine drugs2018

Marine Microalgae with Anti-Cancer Properties.

Kevin A Martínez Andrade, Chiara Lauritano, Giovanna Romano, Adrianna Ianora

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 1 synthesis or guideline pooled it, 275 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Nutraceutical and Antitumoral Potential ofFoods (Basel, Switzerland) · 2026
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  5. Review
  6. Anticancer Activity ofBiomolecules · 2025
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  7. Article
  8. Biology · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Microbiology spectrum · 2025
    Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Monoterpene Hydroxy Lactones Isolated fromMolecules (Basel, Switzerland) · 2024
    Article

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kevin A Martínez AndradeDepartment of Integrative Marine Ecology, Stazione Zoologica Anton Dohrn, 80121 Naples, Italy. kevin.martinez@szn.it.
Chiara LauritanoDepartment of Integrative Marine Ecology, Stazione Zoologica Anton Dohrn, 80121 Naples, Italy. chiara.lauritano@szn.it.ORCID 0000-0003-4580-9594
Giovanna RomanoDepartment of Integrative Marine Ecology, Stazione Zoologica Anton Dohrn, 80121 Naples, Italy. romano@szn.it.
Adrianna IanoraDepartment of Integrative Marine Ecology, Stazione Zoologica Anton Dohrn, 80121 Naples, Italy. adrianna.ianora@szn.it.
Stazione Zoologica Anton Dohrn · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is the leading cause of death globally and finding new therapeutic agents for cancer treatment remains a major challenge in the pursuit for a cure. This paper presents an overview on microalgae with anti-cancer activities. Microalgae are eukaryotic unicellular plants that contribute up to 40% of global primary productivity. They are excellent sources of pigments, lipids, carotenoids, omega-3 fatty acids, polysaccharides, vitamins and other fine chemicals, and there is an increasing demand for their use as nutraceuticals and food supplements. Some microalgae are also reported as having anti-cancer activity. In this review, we report the microalgal species that have shown anti-cancer properties, the cancer cell lines affected by algae and the concentrations of compounds/extracts tested to induce arrest of cell growth. We also report the mediums used for growing microalgae that showed anti-cancer activity and compare the bioactivity of these microalgae with marine anticancer drugs already on the market and in phase III clinical trials. Finally, we discuss why some microalgae can be promising sources of anti-cancer compounds for future development.

Indexed as

Dietary SupplementsAntineoplastic AgentsBiological ProductsCell ProliferationClinical Trials, Phase III as TopicDrug Screening Assays, AntitumorHumansMicroalgaeNeoplasmsAntineoplastic AgentsBiological Productsanti-cancermarine biotechnologymicroalgae

Identifiers

PMID29762545
PMCPMC5983296
OpenAlexW2804861256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.