Trial reportThe British journal of psychiatry : the journal of mental science2018
Long-term clinical and cost-effectiveness of collaborative care (versus usual care) for people with mental-physical multimorbidity: cluster-randomised trial.
Trial report in The British journal of psychiatry : the journal of mental science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 8 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Multimorbidity patterns and mental health in late life: a systematic review of longitudinal studies.European geriatric medicine · 2026Pooled it
- Psychological interventions for depression and anxiety in patients with coronary heart disease, heart failure or atrial fibrillation.The Cochrane database of systematic reviews · 2024Pooled it
- Models for delivery and co-ordination of primary or secondary health care (or both) to older adults living in aged care facilities.The Cochrane database of systematic reviews · 2024Pooled it
- Economic evaluations of interventional opportunities for the management of mental-physical multimorbidity: a systematic review.BMJ open · 2023Pooled it
- Experiences of treatment-resistant mental health conditions in primary care: a systematic review and thematic synthesis.BMC primary care · 2022Pooled it
- The effectiveness of enhanced evidence-based care for depressive disorders: a meta-analysis of randomized controlled trials.Translational psychiatry · 2021Pooled it
- Cost and effects of integrated care: a systematic literature review and meta-analysis.The European journal of health economics : HEPAC : health economics in prevention and care · 2020Pooled it
- The Effectiveness of Patient-Centred Medical Home-Based Models of Care versus Standard Primary Care in Chronic Disease Management: A Systematic Review and Meta-Analysis of Randomised and Non-Randomised Controlled Trials.International journal of environmental research and public health · 2020Pooled it
- Cost-effectiveness of community-based integrated care model for patients with diabetes and depressive symptoms.Nature communications · 2025Trial
- Cost-Effectiveness of a Collaborative Care Model Among Patients With Type 2 Diabetes and Depression in India.Diabetes care · 2023Trial
- Psychological intervention, antipsychotic medication or a combined treatment for adolescents with a first episode of psychosis: the MAPS feasibility three-arm RCT.Health technology assessment (Winchester, England) · 2021Trial
- Developing a psychosomatic medicine curriculum for general practice residents: a proof-of-concept study using Kern's Six-Step Approach.BMC medical education · 2026Article
- Mental health and kidney disease.Nature reviews. Nephrology · 2026Review
- Community-based management strategies for adults with multimorbidity: a systematic review of clinical and patient-centred outcomes.BMJ public health · 2026Article
- The potential for clinical pharmacists to support older people with dementia in the community: A qualitative interview study.British journal of clinical pharmacology · 2025Article
- Integrating Patient Choice and Collaborative Care Managers to Implement eHealth Tools in Depression: Self-Report Pilot Study.Journal of participatory medicine · 2025Article
- Multimorbidity Management: A Scoping Review of Interventions and Health Outcomes.International journal of environmental research and public health · 2025Article
- Enhancing Psychosomatic Medicine Skills in General Practitioners: Insights from Ecological Systems Theory.International journal of general medicine · 2025Article
- Healing the Whole: An International Review of the Collaborative Care Model between Primary Care and Psychiatry.Healthcare (Basel, Switzerland) · 2024Review
- Integrating depression and acute coronary syndrome care in low resource hospitals in China: the I-CARE randomised clinical trial.The Lancet regional health. Western Pacific · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCollaborative care can support the treatment of depression in people with long-term conditions, but long-term benefits and costs are unknown.AimsTo explore the long-term (24-month) effectiveness and cost-effectiveness of collaborative care in people with mental-physical multimorbidity.
methodA cluster randomised trial compared collaborative care (integrated physical and mental healthcare) with usual care for depression alongside diabetes and/or coronary heart disease. Depression symptoms were measured by the symptom checklist-depression scale (SCL-D13). The economic evaluation was from the perspective of the English National Health Service.
results191 participants were allocated to collaborative care and 196 to usual care. At 24 months, the mean SCL-D13 score was 0.27 (95% CI, -0.48 to -0.06) lower in the collaborative care group alongside a gain of 0.14 (95% CI, 0.06-0.21) quality-adjusted life-years (QALYs). The cost per QALY gained was £13 069.
conclusionsIn the long term, collaborative care reduces depression and is potentially cost-effective at internationally accepted willingness-to-pay thresholds.Declaration of interestNone.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.