Evidence map›Paper›PMID 29761424›Full record

ArticleEuropean journal of epidemiology2018

Dietary intake of total polyphenol and polyphenol classes and the risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.

Raul Zamora-Ros, Valerie Cayssials, Mazda Jenab, Joseph A Rothwell, Veronika Fedirko, Krasimira Aleksandrova, Anne Tjønneland, Cecilie Kyrø, Kim Overvad, Marie-Christine Boutron-Ruault and 36 more

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In one paragraph

Article in European journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 59 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

46 authors at 20 institutions in 13 countries.

Raul Zamora-RosUnit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), Av Gran Via 199-203, 08908, L'Hospitalet De Llobregat, Barcelona, Spain. rzamora@iconcologia.net.ORCID http://orcid.org/0000-0002-6236-6804
Valerie CayssialsUnit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), Av Gran Via 199-203, 08908, L'Hospitalet De Llobregat, Barcelona, Spain.
Mazda JenabNutrition and Metabolism Section, International Agency for Research on Cancer (IARC), Lyon, France.
Joseph A RothwellNutrition and Metabolism Section, International Agency for Research on Cancer (IARC), Lyon, France.
Veronika FedirkoRollins School of Public Health, Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Krasimira AleksandrovaDepartment of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.
Anne TjønnelandDanish Cancer Society Research Center, Copenhagen, Denmark.
Cecilie KyrøDanish Cancer Society Research Center, Copenhagen, Denmark.
Kim OvervadDepartment of Public Health, Section for Epidemiology, Aarhus University, Aarhus, Denmark.
Marie-Christine Boutron-RuaultCESP (Centre de Recherche en Epidémiologie et Santé des Populations), Université Paris-Sud, UVSQ, INSERM, Université Paris-Saclay, Villejuif, France.
Franck CarbonnelCESP (Centre de Recherche en Epidémiologie et Santé des Populations), Université Paris-Sud, UVSQ, INSERM, Université Paris-Saclay, Villejuif, France.
Yahya Mahamat-SalehCESP (Centre de Recherche en Epidémiologie et Santé des Populations), Université Paris-Sud, UVSQ, INSERM, Université Paris-Saclay, Villejuif, France.
Rudolf KaaksDivision of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.
Tilman KühnDivision of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.
Heiner BoeingDepartment of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.
Antonia TrichopoulouHellenic Health Foundation, Athens, Greece.
Elissavet ValanouHellenic Health Foundation, Athens, Greece.
Effie VasilopoulouHellenic Health Foundation, Athens, Greece.
Giovanna MasalaCancer Risk Factors and Life-Style Epidemiology Unit, Cancer Research and Prevention Institute - ISPO, Florence, Italy.
Valeria PalaEpidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Salvatore PanicoDepartment of Clinical and Experimental Medicine, Federico II University, Naples, Italy.
Rosario TuminoCancer Registry and Histopathology Unit, "Civic M.P. Arezzo" Hospital, ASP Ragusa, Italy.
Fulvio RicceriDepartment of Clinical and Biological Sciences, University of Turin, Turin, Italy.
Elisabete WeiderpassDepartment of Community Medicine, Faculty of Health Sciences, UiT, The Artic University of Tromsø, Tromsø, Norway.
Marko LukicDepartment of Community Medicine, Faculty of Health Sciences, UiT, The Artic University of Tromsø, Tromsø, Norway.
Torkjel M SandangerDepartment of Community Medicine, Faculty of Health Sciences, UiT, The Artic University of Tromsø, Tromsø, Norway.
Cristina LasherasDepartment of Functional Biology, Faculty of Medicine, University of Oviedo, Oviedo, Spain.
Antonio AgudoUnit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), Av Gran Via 199-203, 08908, L'Hospitalet De Llobregat, Barcelona, Spain.
Maria-Jose SánchezEscuela Andaluza de Salud Pública, Instituto de Investigación Biosanitaria ibs.Granada. Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain.
Pilar AmianoCIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Carmen NavarroCIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Eva ArdanazCIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Emily SonestedtDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Bodil OhlssonDepartment of Internal Medicine, Skåne University Hospital, Lund University, Malmö, Sweden.
Lena Maria NilssonPublic Health and Clinical Medicine, Nutritional Research, Umeå University, Umeå, Sweden.
Martin RutegårdSurgical and Perioperative Sciences, Umeå University, Umeå, Sweden.
Bas Bueno-de-MesquitaDepartment for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Petra H PeetersDepartment of Epidemiology and Biostatistics, The School of Public Health, Imperial College London, London, UK.
Kay-Thee KhawDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Nicholas J WarehamMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Kathryn BradburyCancer Epidemiology Unit, University of Oxford, Oxford, UK.
Heinz FreislingNutrition and Metabolism Section, International Agency for Research on Cancer (IARC), Lyon, France.
Isabelle RomieuNutrition and Metabolism Section, International Agency for Research on Cancer (IARC), Lyon, France.
Amanda J CrossDepartment of Epidemiology and Biostatistics, The School of Public Health, Imperial College London, London, UK.
Paolo VineisDepartment of Epidemiology and Biostatistics, The School of Public Health, Imperial College London, London, UK.
Augustin ScalbertNutrition and Metabolism Section, International Agency for Research on Cancer (IARC), Lyon, France.
Centre international de recherche sur le cancer · FRInstitut d'Investigació Biomédica de Bellvitge · ESUniversité Paris-Sud · FRDanish Cancer Society · DKGerman Cancer Research Center · DEGerman Institute of Human Nutrition · DEImperial College London · GBLund University · SENational and Kapodistrian University of Athens · GRUiT The Arctic University of Norway · NOUmeå University · SEUniversity Medical Center Utrecht · NLUniversity of Cambridge · GBAarhus University · DKAzienda Usl 8 Arezzo · ITBasque Government · ESEmory University · USFederico II University Hospital · ITFondazione IRCCS Istituto Nazionale dei Tumori · ITHellenic Health Foundation · GR

Funding

Cancer Research UK 25004Cancer Research UK A16491Cancer Research UK A19170Medical Research Council MC_UU_12015/1Medical Research Council MR/M012190/1Medical Research Council MR/N003284/1World Health Organization 001
6 · The paper itself

Abstract

Polyphenols may play a chemopreventive role in colorectal cancer (CRC); however, epidemiological evidence supporting a role for intake of individual polyphenol classes, other than flavonoids is insufficient. We evaluated the association between dietary intakes of total and individual classes and subclasses of polyphenols and CRC risk and its main subsites, colon and rectum, within the European Prospective Investigation into Cancer and Nutrition (EPIC) study. The cohort included 476,160 men and women from 10 European countries. During a mean follow-up of 14 years, there were 5991 incident CRC cases, of which 3897 were in the colon and 2094 were in the rectum. Polyphenol intake was estimated using validated centre/country specific dietary questionnaires and the Phenol-Explorer database. In multivariable-adjusted Cox regression models, a doubling in total dietary polyphenol intake was not associated with CRC risk in women (HR

Indexed as

Nutrition AssessmentAdultAgedCoffeeCohort StudiesColorectal NeoplasmsEuropeFemaleFollow-Up StudiesHumansMaleMiddle AgedPolyphenolsProspective StudiesSurveys and QuestionnairesTeaCoffeePolyphenolsTeaColorectal cancerDietEPICIntakePolyphenolsProspective cohort

Identifiers

PMID29761424
PMCPMC6760973
OpenAlexW2804450233

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.