ArticleEuropean journal of nutrition2019
High sodium intake and sodium to potassium ratio may be linked to subsequent increase in vascular damage in adults aged 40 years and older: the Korean multi-rural communities cohort (MRCohort).
Article in European journal of nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Further evidence that methods based on spot urine samples should not be used to examine sodium-disease relationships from the Science of Salt: A regularly updated systematic review of salt and health outcomes (November 2018 to August 2019).Journal of clinical hypertension (Greenwich, Conn.) · 2020Pooled it
- Dietary Sodium Intake and Health Indicators: A Systematic Review of Published Literature between January 2015 and December 2019.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- Current Data on Dietary Sodium, Arterial Structure and Function in Humans: A Systematic Review.Nutrients · 2019Pooled it
- Dietary Sodium Consumption and 3-Year Progression of Subclinical Arterial Damage in Adults with Cardiovascular Risk Factors.Nutrients · 2025Article
- Sustainability and cost of typical and heart-healthy dietary patterns in Australia.American heart journal plus : cardiology research and practice · 2024Article
- Comparative evaluation of non-invasive tests for risk stratification for cause specific mortality in at-risk population of hepatic fibrosis.Scientific reports · 2024Article
- Article
- Dietary sodium to potassium ratio is an independent predictor of cardiovascular events: a longitudinal follow-up study.BMC public health · 2023Article
- The association of arterial stiffness with estimated excretion levels of urinary sodium and potassium and their ratio in Chinese adults.Journal of human hypertension · 2023Article
- Dietary macrominerals: Updated review of their role and orchestration in human nutrition throughout the life cycle with sex differences.Current research in food science · 2023Review
- Sodium intake and the risk of various types of cardiovascular diseases: a Mendelian randomization study.Frontiers in nutrition · 2023Article
- Pan-cerebral sodium elevations in vascular dementia: Evidence for disturbed brain-sodium homeostasis.Frontiers in aging neuroscience · 2022Article
- Contrasting Sodium and Potassium Perturbations in the Hippocampus Indicate Potential NaFrontiers in aging neuroscience · 2022Article
- Global Trends (1961-2017) in Human Dietary Potassium Supplies.Nutrients · 2021Article
- A Relationship between Dietary Patterns and Dyslipidemia in Urban-dwelling Middle-Aged Korean Men: Using Korean Genome and Epidemiology Study (KoGES).Clinical nutrition research · 2019Article
- Highlighting of Urinary Sodium and Potassium among Indonesian Schoolchildren Aged 9-12 Years: The Contribution of School Food.Journal of nutrition and metabolism · 2019Article
- Potassium Intake Prevents the Induction of the Renin-Angiotensin System and Increases Medullary ACE2 and COX-2 in the Kidneys of Angiotensin II-Dependent Hypertensive Rats.Frontiers in pharmacology · 2019Article
- Large artery stiffness is associated with salt intake in young healthy black but not white adults: the African-PREDICT study.European journal of nutrition · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
purposeSubclinical vascular damage is a chronic intermediate process in cardiovascular disease (CVD) and high sodium (Na) has been regarded as an adverse factor in subclinical vascular health; however, the longitudinal relationship between Na intake and subclinical vascular damage has not been studied. We aimed to evaluate the longitudinal relationship of dietary Na intake and sodium to potassium ratio (Na:K) with brachial-ankle pulse wave velocity (baPWV) and carotid intima media thickness (cIMT) in healthy adults aged 40 years and older in Korea.
methodsThe present study was based on participants (n = 2145 for baPWV analysis and n = 2494 for cIMT analysis) who visited three times during 2005-2013 (median 5.3 years of follow-up). We used both dietary Na intake and Na:K at baseline and its average (baseline, 2nd, 3rd), which was obtained from food frequency questionnaire (FFQ) as exposure at every visit. baPWV and cIMT levels at the third visit and change from baseline to the third visit were used to represent the level of subclinical vascular damage.
resultsAfter adjustment for potential confounders, significant positive relationships between dietary Na intake and both baPWV
conclusionsIn conclusion, dietary Na intake and Na:K may be positively linked to subsequent baPWV and cIMT levels in adults aged 40 years and older in Korea. Our findings may provide informative evidence on subclinical vascular damage, particularly for populations with relatively high dietary Na intake and low dietary K intake.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.