Evidence map›Paper›PMID 29761109›Full record

ArticleReports of biochemistry & molecular biology2018

Mesenchymal Stem Cells Differentiate to Endothelial Cells Using Recombinant Vascular Endothelial Growth Factor -A.

Mohsen Khaki, Ali Hatef Salmanian, Hamid Abtahi, Ali Ganji, Ghasem Mosayebi

Open access · greenAbstract read
In one paragraph

Article in Reports of biochemistry & molecular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 30 citations in OpenAlex.

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  7. Stem/Progenitor Cells and Related Therapy in Bronchopulmonary Dysplasia.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mohsen KhakiMolecular and Medicine Research Center, Arak University of Medical Sciences, Arak, Iran.
Ali Hatef SalmanianNational Institute for Genetic Engineering and Biotechnology, Tehran. Iran.
Hamid AbtahiMolecular and Medicine Research Center, Arak University of Medical Sciences, Arak, Iran.
Ali GanjiMolecular and Medicine Research Center, Arak University of Medical Sciences, Arak, Iran.
Ghasem MosayebiMolecular and Medicine Research Center, Arak University of Medical Sciences, Arak, Iran.
Arak University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVascular endothelial growth factor-A (VEGF-A), an endothelial cell-specific mitogen produced by various cell types, plays important roles in cell differentiation and proliferation. In this study we investigated the effect of recombinant VEGF-A on differentiation of mesenchymal stem cells (MSCs) to endothelial cells (ECs).

methodsVEGF-A was expressed in

resultsRecombinant VEGF-A was produced in

conclusionRecombinant VEGF-A expressed in a prokaryotic system can induce MSCs differentiation to ECs and can be used in research and likely therapeutic applications.

Indexed as

Cell differentiationEndothelial cellMesenchymal stem cellVascular Endothelial Growth Factor A

Identifiers

PMID29761109
PMCPMC5940356
OpenAlexW2767683707

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.