ArticlePulse (Basel, Switzerland)2018
Associations between Type 2 Diabetes Mellitus and Arterial Stiffness: A Prospective Analysis Based on the Maine-Syracuse Study.
Article in Pulse (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evidence of a Bi-Directional Relationship between Arterial Stiffness and Diabetes: A Systematic Review and Meta-Analysis of Cohort Studies.Current diabetes reviews · 2025Pooled it
- Trial
- Regional cerebral arterial elasticity is associated with cardiovascular health in cognitively healthy older adults.bioRxiv : the preprint server for biology · 2026Article
- Article
- Hypertension in diabetes.Pediatric nephrology (Berlin, Germany) · 2024Article
- Article
- Diabetes, glycemic control and arterial stiffness: a real-world cohort study in the context of predictive, preventive, and personalized medicine.The EPMA journal · 2023Article
- Aortic stiffness effectively risk stratifies diabetic patients with suspected myocardial ischemia undergoing vasodilatory stress perfusion cardiac magnetic resonance.BMC cardiovascular disorders · 2023Article
- Associations of aortic stiffness and intra-aortic flow parameters with epicardial adipose tissue in patients with type-2 diabetes.Frontiers in clinical diabetes and healthcare · 2023Article
- A Triplex Ultrasound Evaluation of Preclinical Changes in Type 2 Diabetes in Foot Arteries.Cureus · 2022Article
- Article
- Association of monocyte-to-high density lipoprotein ratio with arterial stiffness in patients with diabetes.BMC cardiovascular disorders · 2021Article
- Arterial stiffness in type 2 diabetes: determinants and indication of a discriminative value.Clinics (Sao Paulo, Brazil) · 2021Article
- Comparison of ambulatory central hemodynamics and arterial stiffness in patients with diabetic and non-diabetic CKD.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- The Relationship Between Glycemic Control and Concomitant Hypertension on Arterial Stiffness in Type II Diabetes.Vascular health and risk management · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to investigate prospective associations between type 2 diabetes mellitus status and the gold standard non-invasive method for ascertaining arterial stiffness, carotid femoral pulse wave velocity.
methodsThe prospective analysis employed 508 community-dwelling participants (mean age 61 years, 60% women) from the Maine-Syracuse Longitudinal Study. Pulse wave velocity at wave 7 (2006-2010) was compared between those with type 2 diabetes mellitus at wave 6 (2001-2006) (
resultsType 2 diabetes mellitus status was associated with a significantly higher pulse wave velocity (12.5 ± 0.36 vs. 10.4 ± 0.12 m/s). Multivariate adjustment for other cardiovascular risk factors and lifestyle- and pulse wave velocity-related variables did not attenuate the findings. The risk of an elevated pulse wave velocity (≥12 m/s) was over 9 times higher for those with uncontrolled type 2 diabetes mellitus than for those without diabetes (OR 9.14, 95% CI 3.23-25.9,
conclusionsType 2 diabetes mellitus, particularly if uncontrolled, is significantly associated with risk of arterial stiffness later in life. Effective management of diabetes mellitus is an important element of protection from arterial stiffness.
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