ArticlePeerJ2018
Loss anticipation and outcome during the
Article in PeerJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Shared and distinct neural activity during anticipation and outcome of win and loss: A meta-analysis of the monetary incentive delay task.NeuroImage · 2022Pooled it
- Neural substrates of motivational dysfunction across neuropsychiatric conditions: Evidence from meta-analysis and lesion network mapping.Clinical psychology review · 2022Pooled it
- Does losing money truly hurt? The shared neural bases of monetary loss and pain.Human brain mapping · 2022Pooled it
- Subacute effects of ketamine on neural correlates of reward processing.Translational psychiatry · 2026Trial
- Common and Distinct Neural Substrates for Approach- and Avoidance-Motivated Actions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Anterior insula reactivity to loss moderates the association between trait impulsivity and future suicidal ideation in adolescents.Developmental cognitive neuroscience · 2026Article
- Mesocorticolimbic circuitry in episodic migraine: reward- and punishment-related responses and resting-state connectivity.The journal of headache and pain · 2026Article
- Reward circuit function and treatment outcome following vALIC deep brain stimulation in treatment-resistant depression.Molecular psychiatry · 2026Article
- Blunted Ventral Striatal Reactivity to Social Reward Is Associated with More Severe Motivation and Pleasure Deficits in Psychosis.Schizophrenia bulletin · 2025Article
- Identification and External Validation of a Problem Cannabis Risk Network.Biological psychiatry · 2025Article
- Ventromedial prefrontal cortex lesions disrupt learning to reward others.Brain : a journal of neurology · 2025Article
- Addressing Altered Anticipation as a Transdiagnostic Target Through Computational Psychiatry.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Review
- Cross-species translational paradigms for assessing positive valence system as defined by the RDoC matrix.Journal of neurochemistry · 2025Review
- Repetition suppression between monetary loss and social pain.BMC psychology · 2024Article
- Blunted ventral striatal reactivity to social reward is associated with more severe motivation and pleasure deficits in psychosis.Research square · 2024Article
- Altered neural anticipation of reward and loss but not receipt in adolescents with obsessive-compulsive disorder.BMC psychiatry · 2024Article
- Blunted Neurobehavioral Loss Anticipation Predicts Relapse to Stimulant Drug Use.Biological psychiatry · 2024Article
- A multi-sample evaluation of the measurement structure and function of the modified monetary incentive delay task in adolescents.Developmental cognitive neuroscience · 2024Article
- Mechanisms underlying capsulotomy for refractory obsessive-compulsive disorder: neural correlates of negative affect processing overlap with deep brain stimulation targets.Molecular psychiatry · 2023Article
- A neurocognitive model of early onset persistent and desistant antisocial behavior in early adulthood.Frontiers in human neuroscience · 2023Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundReward seeking and avoidance of punishment are key motivational processes. Brain-imaging studies often use the
methodsAll functional neuro-imaging studies using the MIDT in healthy controls were retrieved using PubMed, Google Scholar & EMBASE databases. Functional neuro-imaging data was analyzed using the Seed-based d Mapping Software.
resultsThirty-five studies met the inclusion criteria, comprising 699 healthy adults. In both anticipation and loss outcome phases, participants showed large and robust activations in the bilateral striatum, (anterior) insula, and anterior cingulate gyrus relatively to Loss > Neutral contrast. Although relatively similar activation patterns were observed during the two event types, they differed in the pattern of prefrontal activations: ventro-lateral prefrontal activations were observed during loss anticipation, while medial prefrontal activations were observed during loss receipt. DISCUSSION: Considering that previous meta-analyses highlighted activations in the medial prefrontal cortex/anterior cingulate cortex, the anterior insula and the ventral striatum, the current meta-analysis highlighted the potential specificity of the ventro-lateral prefrontal regions, the median cingulate cortex and the amygdala in the loss events. Future studies can rely on these latter results to examine the neural correlates of loss processing in psychiatric populations characterized by harm avoidance or insensitivity to punishment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.