Evidence map›Paper›PMID 29760845›Full record

Observational studyThe western journal of emergency medicine2018

Ruling out Pulmonary Embolism in Patients with High Pretest Probability.

Murtaza Akhter, Jeffrey Kline, Bikash Bhattarai, Mark Courtney, Christopher Kabrhel

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in The western journal of emergency medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Murtaza AkhterUniversity of Arizona College of Medicine-Phoenix, Maricopa Integrated Health System, Department of Emergency Medicine, Phoenix, Arizona.
Jeffrey KlineIndiana University School of Medicine, Department of Emergency Medicine and Department of Cellular and Integrative Physiology, Indianapolis, Indiana.
Bikash BhattaraiUniversity of Arizona College of Medicine-Phoenix, Maricopa Integrated Health System, Department of Medicine Administration, Phoenix, Arizona.
Mark CourtneyNorthwestern University's Feinberg School of Medicine, Department of Emergency Medicine, Chicago, Illinois.
Christopher KabrhelMassachusetts General Hospital, Department of Emergency Medicine, Center for Vascular Emergencies, Boston, Massachusetts.
Indiana University School of MedicineNorthwestern University · USValleywise Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe American College of Emergency Physicians guidelines recommend more aggressive workup beyond imaging alone in patients with a high pretest probability (PTP) of pulmonary embolism (PE). However, the ability of multiple tests to safely rule out PE in high PTP patients is not known. We sought to measure the ability of negative computed tomography pulmonary angiography (CTPA)

methodsWe analyzed data from a previous prospective observational study conducted in 12 emergency departments (ED). Wells score criteria were entered by providers before final PE testing. PE was diagnosed by imaging on the index ED visit, or within 45 days, demonstrating either PE or deep vein thrombosis (DVT), or if the patient died of PE during the 45-day, follow-up period. Testing threshold was set at 1.8%.

resultsA total of 7,940 patients were enrolled and tested for PE, and 257 had high PTP (Wells >6). Sixteen of these high-risk patients had negative CTPA

conclusionOur analysis suggests that in patients with high PTP of PE, neither negative CTPA by itself nor a negative CTPA

Indexed as

Emergency Service, HospitalPredictive Value of TestsFemaleFibrin Fibrinogen Degradation ProductsHumansMaleMiddle AgedProbabilityProspective StudiesPulmonary EmbolismVenous ThrombosisFibrin Fibrinogen Degradation Products

Identifiers

PMID29760845
PMCPMC5942014
OpenAlexW2790075728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.