ArticleHereditary cancer in clinical practice2018
Challenges in recruiting African-American women for a breast cancer genetics study.
Article in Hereditary cancer in clinical practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effective Recruitment Strategies Utilized to Examine Dietary Practices of Blacks in New York City in the Midst of the COVID-19 Pandemic.Journal of racial and ethnic health disparities · 2024Pooled it
- "Lord Knows What's Being Done with My Blood!": Black Women's Perceptions of Biospecimen Donation for Clinical Research in the United States.Journal of racial and ethnic health disparities · 2025Article
- Using genome and transcriptome data from African-ancestry female participants to identify putative breast cancer susceptibility genes.Nature communications · 2024Article
- Review of genetic and pharmacogenetic differences in cytotoxic and targeted therapies for pancreatic cancer in African Americans.Journal of the National Medical Association · 2023Review
- Lessons Learned from the Pilot Phase of a Population-Wide Genomic Screening Program: Building the Base to Reach a Diverse Cohort of 100,000 Participants.Journal of personalized medicine · 2022Article
- Cascade screening for glaucoma in high-risk family members of African-Caribbean glaucoma patients in an urban population in London.The British journal of ophthalmology · 2022Article
- Challenges Faced by Behavioral Genetic Studies: Researchers Perspective from the MENA Region.Current genomics · 2021Article
- Increased ease of access to genetic counseling for low-income women with breast cancer using a point of care screening tool.Journal of community genetics · 2021Article
- Building and Sustaining a Community Advisory Board of African American Older Adults as the Foundation for Volunteer Research Recruitment and Retention in Health Sciences.Ethnicity & disease · 2020Article
- Sistas Taking a Stand for Breast Cancer Research (STAR) Study: A Community-Based Participatory Genetic Research Study to Enhance Participation and Breast Cancer Equity among African American Women in Memphis, TN.International journal of environmental research and public health · 2018Article
- Engaging and Recruiting Black Men With Stroke or TIA in a Randomized Clinical Trial Conducted: Addressing Research Barriers and Developing Solutions for Successful Engagement.American journal of men's healthArticle
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6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAfrican-American women, especially in the southern United States, are underrepresented in cancer genetics research. A study was designed to address this issue by investigating the germline mutation rate in African-American women in Arkansas with a personal and/or family history of breast cancer. Women were tested for these mutations using a large panel of breast cancer susceptibility genes. In this analysis, we discuss the challenges encountered in recruiting African-American women from an existing biorepository to participate in this study.
methodsWe attempted to contact 965 African-American women with a personal and/or family history of breast cancer who participated in Spit for the Cure (SFTC) between 2007 and 2013 and provided consent to be recontacted. The SFTC participants were invited by telephone and email to participate in the genetic study. Enrollment required completion of a phone interview to obtain a family and medical history and return of a signed consent form.
resultsAmong eligible SFTC participants, 39.6% (382/965) were able to be contacted with the phone numbers and email addresses they provided. Of these, 174 (45.5%) completed a phone interview and returned a signed consent form. Others were not able to be contacted (
conclusionsRecruiting African-American women into our breast cancer genetics study proved challenging primarily due to difficulty establishing contact with potential participants. Given their prior participation in breast cancer research, we anticipated that this would be a highly motivated population. Indeed, when we were able to contact SFTC participants, only 14.9% declined to participate in our study. Innovative communication, retention, and recruitment strategies are needed in future studies to address the recruitment challenges we faced.
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