Evidence map›Paper›PMID 29760810›Full record

ArticleClinical epigenetics2018

DNA methylation and socioeconomic status in a Mexican-American birth cohort.

Eric S Coker, Robert Gunier, Karen Huen, Nina Holland, Brenda Eskenazi

Abstract read
In one paragraph

Article in Clinical epigenetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
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  11. Article
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  13. Observational
  14. Review
  15. Review
  16. Article
  17. Neighborhood Environment and DNA Methylation: Implications for Cardiovascular Disease Risk.Journal of urban health : bulletin of the New York Academy of Medicine · 2019
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eric S Coker1Center for Environmental Research and Children's Health (CERCH), School of Public Health, University of California, Berkeley, CA USA.
Robert Gunier1Center for Environmental Research and Children's Health (CERCH), School of Public Health, University of California, Berkeley, CA USA.
Karen Huen1Center for Environmental Research and Children's Health (CERCH), School of Public Health, University of California, Berkeley, CA USA.
Nina Holland1Center for Environmental Research and Children's Health (CERCH), School of Public Health, University of California, Berkeley, CA USA.
Brenda Eskenazi1Center for Environmental Research and Children's Health (CERCH), School of Public Health, University of California, Berkeley, CA USA.

Funding

Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
Project C: Epigenetic Effects of DDT/E and PBDEs on PubertyP01ES009605 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI ESKENAZI, BRENDA · 1999 to 2015
$11.2M
Molecular Mechanisms of Obesity in Children Exposed to Phthalates in UteroR01ES021369 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HOLLAND, NINA T · 2013 to 2017
$3.1M
Long-term sequelae of early life pesticide exposure in the CHAMACOS birth cohortUG3OD023356 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI ESKENAZI, BRENDA · 2016 to 2017
$2.6M
PON Epigenetics and Neurodevelopment in ChildrenR01ES023067 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HOLLAND, NINA T · 2014 to 2017
$1.3M
FIC NIH HHS D43 TW010540NIEHS NIH HHS P01 ES009605NIEHS NIH HHS R01 ES021369NIEHS NIH HHS R01 ES023067NIH HHS UG3 OD023356
6 · The paper itself

Abstract

Background: Maternal social environmental stressors during pregnancy are associated with adverse birth and child developmental outcomes, and epigenetics has been proposed as a possible mechanism for such relationships. Methods: In a Mexican-American birth cohort of 241 maternal-infant pairs, cord blood samples were measured for repeat element DNA methylation ( Results: After adjusting for confounders, living in the most impoverished neighborhoods was associated with higher cord blood LINE-1 methylation ( Conclusion: Our findings indicate a small yet unexpected positive association between neighborhood-level poverty during pregnancy and methylation of repetitive element DNA in infant cord blood and that this association is possibly modified by diet quality during pregnancy. However, our null findings for other adverse SES indicators do not provide strong evidence for an adverse association between early-life socioeconomic environment and repeat element DNA methylation in infants.

Indexed as

Alu ElementsDNA MethylationLong Interspersed Nucleotide ElementsCohort StudiesEpigenesis, GeneticFemaleHumansInfant, NewbornMexican AmericansNutrition SurveysPregnancySocial ClassDietEpigeneticsMethylationRepeat elementSocial adversitySocioeconomic status

Identifiers

PMID29760810
PMCPMC5941629

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.