Evidence map›Paper›PMID 29760652›Full record

ArticleFrontiers in molecular neuroscience2018

Cadherins Interact With Synaptic Organizers to Promote Synaptic Differentiation.

Masahito Yamagata, Xin Duan, Joshua R Sanes

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.

  1. Pooled it
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  8. Nervous system-wide analysis of allScience advances · 2025
    Article
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  10. Review
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  15. Cadherin-13 Maintains Retinotectal Synapses via Transneuronal Interactions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Masahito YamagataCenter for Brain Science and Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, United States.
Xin DuanCenter for Brain Science and Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, United States.
Joshua R SanesCenter for Brain Science and Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, United States.
Harvard University · US

Funding

Combinatorial roles of cadherins in retinal circuit assembly.R01EY022073 · NEI · HARVARD UNIVERSITY · PI SANES, JOSHUA R · 2012 to 2020
$3.7M
Mechanisms Underlying Type II Cadherin Guided Assembly of Retinal CircuitsR01EY030138 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Xin Duan · 2020 to 2026
$3.2M
NEI NIH HHS R01 EY022073NEI NIH HHS R01 EY030138
6 · The paper itself

Abstract

Classical cadherins, a set of ~20 related recognition and signaling molecules, have been implicated in many aspects of neural development, including the formation and remodeling of synapses. Mechanisms underlying some of these steps have been studied by expressing N-cadherin (

Indexed as

adhesioncadherinHEK293LRRtm2N-cadherinneurexinneuroliginsynaptogenesis

Identifiers

PMID29760652
PMCPMC5936767
OpenAlexW2803034248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.