Evidence map›Paper›PMID 29760651›Full record

ArticleFrontiers in molecular neuroscience2018

Human DNA Helicase B as a Candidate for Unwinding Secondary CGG Repeat Structures at the

Gulfem D Guler, Zev Rosenwaks, Jeannine Gerhardt

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Mechanisms of theInternational journal of molecular sciences · 2022
    Review
  4. Human HELB is a processive motor protein that catalyzes RPA clearance from single-stranded DNA.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gulfem D GulerCelgene Quanticel Research, San Francisco, CA, United States.
Zev RosenwaksThe Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, Cornell University, New York, NY, United States.
Jeannine GerhardtThe Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, Cornell University, New York, NY, United States.
Cornell University · US

Funding

Identification of compounds stabilizing the GAA repeats in Friedreich’s ataxia cellsR03NS106216 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI GERHARDT, JEANNINE · 2018 to 2019
$170k
NINDS NIH HHS R03 NS106216
6 · The paper itself

Abstract

The fragile X syndrome (FXS) is caused by a CGG repeat expansion at the

Indexed as

fragile sitesfragile X syndromehelicasesrepeatsreplicationsecondary structure

Identifiers

PMID29760651
PMCPMC5936766
OpenAlexW2802422572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.