Evidence map›Paper›PMID 29760575›Full record

ReviewEye and brain2018

The development of human visual cortex and clinical implications.

Caitlin R Siu, Kathryn M Murphy

Open access · goldAbstract readReview
In one paragraph

Review in Eye and brain, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 130 citations in OpenAlex.

  1. Amblyopia: progress and promise of functional magnetic resonance imaging.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Pooled it
  2. Improvements in Static Balance Following an Oculomotor Exercise Program in Athletes.Journal of musculoskeletal & neuronal interactions · 2026
    Trial
  3. Article
  4. Assessing visual and refractive outcomes of subretinal fluid detected by handheld swept-source optical coherence tomography in full-term newborns.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2026
    Article
  5. Article
  6. Article
  7. Visual function and autism spectrum disorder.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  8. Article
  9. Article
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  18. Article
  19. The Prevalence and Risk Factors of Abnormal Vision Among Preschool Children.Pediatric health, medicine and therapeutics · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Caitlin R SiuMcMaster Integrative Neuroscience Discovery and Study (MiNDS) Program, McMaster University, Hamilton, ON, Canada.
Kathryn M MurphyMcMaster Integrative Neuroscience Discovery and Study (MiNDS) Program, McMaster University, Hamilton, ON, Canada.
McMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The primary visual cortex (V1) is the first cortical area that processes visual information. Normal development of V1 depends on binocular vision during the critical period, and age-related losses of vision are linked with neurobiological changes in V1. Animal studies have provided important details about the neurobiological mechanisms in V1 that support normal vision or are changed by visual diseases. There is very little information, however, about those neurobiological mechanisms in human V1. That lack of information has hampered the translation of biologically inspired treatments from preclinical models to effective clinical treatments. We have studied human V1 to characterize the expression of neurobiological mechanisms that regulate visual perception and neuroplasticity. We have identified five stages of development for human V1 that start in infancy and continue across the life span. Here, we describe these stages, compare them with visual and anatomical milestones, and discuss implications for translating treatments for visual disorders that depend on neuroplasticity of V1 function.

Indexed as

amblyopiadevelopmentGABAergicglutamatergichuman visual cortexreceptorssynaptic plasticity

Identifiers

PMID29760575
PMCPMC5937627
OpenAlexW2802723470

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.