Evidence map›Paper›PMID 29760550›Full record

ArticleInternational journal of nanomedicine2018

Synergistic antifungal effect of chitosan-stabilized selenium nanoparticles synthesized by pulsed laser ablation in liquids against

Humberto H Lara, Gregory Guisbiers, Jonathan Mendoza, Lawrence C Mimun, Brandy A Vincent, Jose L Lopez-Ribot, Kelly L Nash

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 94 citations in OpenAlex.

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  9. Evaluating the anti-Journal of dental research, dental clinics, dental prospects · 2024
    Article
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  11. Antifungal therapy ofBiofilm · 2023
    Article
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  14. Article
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  17. Frontiers in cellular and infection microbiology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Humberto H LaraDepartment of Biology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX, USA.
Gregory GuisbiersDepartment of Physics and Astronomy, University of Arkansas at Little Rock, Little Rock, AR, USA.
Jonathan MendozaDepartment of Physics and Astronomy, The University of Texas at San Antonio, San Antonio, TX, USA.
Lawrence C MimunUS Army Engineer Research & Development Center, Vicksburg, MS, USA.
Brandy A VincentDepartment of Physics and Astronomy, The University of Texas at San Antonio, San Antonio, TX, USA.
Jose L Lopez-RibotDepartment of Biology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX, USA.
Kelly L NashDepartment of Physics and Astronomy, The University of Texas at San Antonio, San Antonio, TX, USA.
The University of Texas at San Antonio · USTexas Center for Infectious Disease · USUniversity of Arkansas at Little Rock · US

Funding

UTSA RISE Research Training ProgramR25GM060655 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI BAREA-RODRIGUEZ, EDWIN J · 2000 to 2022
$21.6M
RCMI Center for Interdiscplinary Health Research CIHRG12MD007591 · NIMHD · UNIVERSITY OF TEXAS SAN ANTONIO · PI PERRY, GEORGE · 2012 to 2016
$10.4M
NIGMS NIH HHS R25 GM060655NIMHD NIH HHS G12 MD007591
6 · The paper itself

Abstract

background

methodsIn this study, we report, for the first time, the synthesis of selenium nanoparticles by irradiating selenium pellets by nanosecond pulsed laser ablation in liquid chitosan as a capping agent. Synergy of the fungicidal effect of selenium nanoparticles and chitosan was quantified by the combination index theorem of Chou-Talalay.

resultsThis drug combination resulted in a potent fungicidal effect against a preformed

conclusionThese chitosan-stabilized selenium nanoparticles could be used for ex vivo applications such as sterilizers for surfaces and biomedical devices.

Indexed as

Antifungal AgentsBiofilmsCandida albicansCell LineChitosanDose-Response Relationship, DrugDrug Therapy, CombinationHumansLasersMicrobial Sensitivity TestsNanoparticlesNanotechnologySeleniumAntifungal AgentsChitosanSeleniumbiofilmCandida albicanschitosanlaser ablation in liquidsselenium nanoparticlessynergy

Identifiers

PMID29760550
PMCPMC5937483
OpenAlexW2800887222

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.