Evidence map›Paper›PMID 29760546›Full record

Observational studyWorld journal of gastroenterology2018

Thiopurines are negatively associated with anthropometric parameters in pediatric Crohn's disease.

Neera Gupta, Robert H Lustig, Cewin Chao, Eric Vittinghoff, Howard Andrews, Cheng-Shiun Leu

Open access · hybridAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Neera GuptaDivision of Gastroenterology and Nutrition, Department of Pediatrics, Weill Cornell Medicine, New York, NY 10021, United States. neg9020@med.cornell.edu.
Robert H LustigDivision of Endocrinology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94158, United States.
Cewin ChaoDepartment of Nutrition and Food Services, University of California, San Francisco, San Francisco, CA 94143, United States.
Eric VittinghoffDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA 94158, United States.
Howard AndrewsDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY 10032, United States.
Cheng-Shiun LeuDepartment of Biostatistics, Columbia University Medical Center, New York, NY 10032, United States.
University of California, San Francisco · USColumbia University · USColumbia University Irving Medical Center · US

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
Gender Differences in Growth in Pediatric Patients with Crohn's DiseaseK23DK077734 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GUPTA, NEERA · 2007 to 2011
$681k
NCRR NIH HHS UL1 RR024131NIDDK NIH HHS K23 DK077734
6 · The paper itself

Abstract

aimTo determine the distribution of anthropometric parameter (AP)-

methodsCD patients [< chronological age (CA) 21 years] were enrolled in a cross-sectional study. Descriptive statistics were generated for participants' demographic characteristics and key variables of interest. Paired

resultsMean CA at the time of the study visit was 15.3 ± 3.5 (SD; range = 4.8-20.7) years. Mean triceps skinfold (

conclusionOur results suggest poor efficacy of thiopurines and a possible sex difference in statural growth response to infliximab in pediatric CD. Prospective longitudinal studies are required.

Indexed as

AnthropometryAdolescentAdultAzathioprineBiomarkersBody CompositionBone DevelopmentChildChild, PreschoolCrohn DiseaseCross-Sectional StudiesFemaleHumansImmunosuppressive AgentsInfliximabMaleAzathioprineBiomarkersImmunosuppressive AgentsInfliximabMercaptopurineAzathioprine/6-mercaptopurineBiologicsInflammatory bowel diseaseNutrition

Identifiers

PMID29760546
PMCPMC5949716
OpenAlexW2802857047

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.