ArticleNature communications2018
Two-photon imaging of neuronal activity in motor cortex of marmosets during upper-limb movement tasks.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed, 105 citations in OpenAlex.
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- Deciphering Neural Mechanisms Underlying Marmoset Dynamic Natural Behaviors Using a Miniaturized Wireless Large-Scale Coverage Neural Recorder.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
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- Neural Recording Chambers for Long-Term Access to Brain Tissue.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- TWINKLE: An open-source two-photon microscope for teaching and research.bioRxiv : the preprint server for biology · 2025Article
- What can ANS signals tell us about motor learning? An implication for better assessment of cognitive contribution to motor learning.Frontiers in behavioral neuroscience · 2025Article
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- ARViS: a bleed-free multi-site automated injection robot for accurate, fast, and dense delivery of virus to mouse and marmoset cerebral cortex.Nature communications · 2024Article
- Dynamics of directional motor tuning in the primate premotor and primary motor cortices during sensorimotor learning.Nature communications · 2024Article
- Large-scale cranial window for in vivo mouse brain imaging utilizing fluoropolymer nanosheet and light-curable resin.Communications biology · 2024Article
- Mesoscopic calcium imaging in a head-unrestrained male non-human primate using a lensless microscope.Nature communications · 2024Article
- Change detection in the primate auditory cortex through feedback of prediction error signals.Nature communications · 2023Article
- Article
- The neurobiology of vocal communication in marmosets.Annals of the New York Academy of Sciences · 2023Review
- Upper limb modeling and motion extraction based on multi-space-fusion.Scientific reports · 2023Article
- 2-Photon imaging of fluorescent proteins in living swine.Scientific reports · 2023Article
- Face-Selective Patches in Marmosets Are Involved in Dynamic and Static Facial Expression Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
Corrections and comments
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Authors and funding
15 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two-photon imaging in behaving animals has revealed neuronal activities related to behavioral and cognitive function at single-cell resolution. However, marmosets have posed a challenge due to limited success in training on motor tasks. Here we report the development of protocols to train head-fixed common marmosets to perform upper-limb movement tasks and simultaneously perform two-photon imaging. After 2-5 months of training sessions, head-fixed marmosets can control a manipulandum to move a cursor to a target on a screen. We conduct two-photon calcium imaging of layer 2/3 neurons in the motor cortex during this motor task performance, and detect task-relevant activity from multiple neurons at cellular and subcellular resolutions. In a two-target reaching task, some neurons show direction-selective activity over the training days. In a short-term force-field adaptation task, some neurons change their activity when the force field is on. Two-photon calcium imaging in behaving marmosets may become a fundamental technique for determining the spatial organization of the cortical dynamics underlying action and cognition.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.