ArticleNature communications2018
Evolutionary instability of CUG-Leu in the genetic code of budding yeasts.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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Who cites it
62 citing papers in PubMed.
- Article
- Review
- Regions of low gene expression promote maintenance and adaptation of horizontally acquired genes in yeasts.Communications biology · 2026Article
- Chromosome-scale genome assembly and characterization of Saccharomycopsis schoenii, a necrotrophic predatory yeast.G3 (Bethesda, Md.) · 2026Article
- Biosynthesis, Regulation, and Biotechnological Production Strategies of Riboflavin (Vitamin BPharmaceuticals (Basel, Switzerland) · 2026Review
- Novel killer yeasts and toxins from the gardens of fungus-growing ants.Applied and environmental microbiology · 2026Article
- Hog1 MAP kinase modulates early riboflavin accumulation under low-pH and saline conditions inFrontiers in microbiology · 2026Article
- Genomic Insights ofOpen forum infectious diseases · 2026Review
- Predicting the Structural Effects of CUG Codon Translation on Uncharacterized Proteins inJournal of fungi (Basel, Switzerland) · 2025Article
- Ancient origin and high diversity of zymocin-like killer toxins in the budding yeast subphylum.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Molecular evolution of the members of the Snq2/Pdr18 subfamily of Pdr transporters in the Hemiascomycete yeasts.FEMS yeast research · 2025Article
- Lignocellulosic biomass fermentation: a roadmap for Candida famata and Ogataea polymorpha.FEMS yeast research · 2025Review
- Genomic factors shaping codon usage across the Saccharomycotina subphylum.G3 (Bethesda, Md.) · 2024Article
- Candida boidinii isolates from olive curation water: a promising platform for methanol-based biomanufacturing.AMB Express · 2024Article
- Evolution of the Genetic Code in the Ascoideales (CUG-Ser2) Yeast Clade: The Ancestral tRNA-Leu(CAG) Gene Is Retained in Most Saccharomycopsis Species but Is Nonessential and Not Used for Translation.Genome biology and evolution · 2024Article
- Re-routing MAP kinase signaling for penetration peg formation in predator yeasts.PLoS pathogens · 2024Article
- Use of the Saccharomycopsis schoenii MET17 promoter for regulated heterologous gene expression.Current genetics · 2024Article
- The promise and pitfalls of synteny in phylogenomics.PLoS biology · 2024Article
- Robust genetic codes enhance protein evolvability.PLoS biology · 2024Article
- Genomic factors shape carbon and nitrogen metabolic niche breadth across Saccharomycotina yeasts.Science (New York, N.Y.) · 2024Article
2 more citing papers are in PubMed but not listed here.
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14 authors.
Funding
Abstract
The genetic code used in nuclear genes is almost universal, but here we report that it changed three times in parallel during the evolution of budding yeasts. All three changes were reassignments of the codon CUG, which is translated as serine (in 2 yeast clades), alanine (1 clade), or the 'universal' leucine (2 clades). The newly discovered Ser2 clade is in the final stages of a genetic code transition. Most species in this clade have genes for both a novel tRNA
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