Evidence that UBASH3 is a causal gene for type 1 diabetes.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed.

1. The Ubiquitin-Associated and SH3 Domain-Containing Proteins (UBASH3) Family in Mammalian Development and Immune Response.International journal of molecular sciences · 2024
   Review
2. The genetics of autoimmune Addison disease: past, present and future.Nature reviews. Endocrinology · 2022
   Review
3. An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci.Nature genetics · 2021
   Article
4. T Cell Receptor Genotype andGenes · 2021
   Article
5. An unexpected 2-histidine phosphoesterase activity of suppressor of T-cell receptor signaling protein 1 contributes to the suppression of cell signaling.The Journal of biological chemistry · 2020
   Article
6. Rheumatoid Arthritis Patients, Both Newly Diagnosed and Methotrexate Treated, Show More DNA Methylation Differences in CD4Frontiers in immunology · 2020
   Article
7. Approaches and advances in the genetic causes of autoimmune disease and their implications.Nature immunology · 2018
   Review
8. Immune Dysregulation and the Increased Risk of Complications and Mortality Following Respiratory Tract Infections in Adults With Down Syndrome.Frontiers in immunology
   Review

Corrections and comments

• Comment on
  UBASH3A Mediates Risk for Type 1 Diabetes Through Inhibition of T-Cell Receptor-Induced NF-κB Signaling.2017
• Comment on
  Molecular-genetic characterization of common, noncoding UBASH3A variants associated with type 1 diabetes.2018

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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