Evidence map›Paper›PMID 29760429›Full record

ArticleScientific reports2018

Novel canine circovirus strains from Thailand: Evidence for genetic recombination.

Chutchai Piewbang, Wendy K Jo, Christina Puff, Erhard van der Vries, Sawang Kesdangsakonwut, Anudep Rungsipipat, Jochen Kruppa, Klaus Jung, Wolfgang Baumgärtner, Somporn Techangamsuwan and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 82 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Chutchai PiewbangDepartment of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand.
Wendy K JoResearch Center for Emerging Infections and Zoonoses, University of Veterinary Medicine (TiHo-RIZ), Bünteweg 17, Hannover, 30559, Germany.ORCID 0000-0003-1253-9540
Christina PuffDepartment of Pathology, University of Veterinary Medicine, Bünteweg 17, Hannover, 30559, Germany.
Erhard van der VriesResearch Center for Emerging Infections and Zoonoses, University of Veterinary Medicine (TiHo-RIZ), Bünteweg 17, Hannover, 30559, Germany.
Sawang KesdangsakonwutDepartment of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand.
Anudep RungsipipatDepartment of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand.
Jochen KruppaInstitute for Animal Breeding and Genetics, University of Veterinary Medicine, Bünteweg 17p, Hannover, 30559, Germany.
Klaus JungInstitute for Animal Breeding and Genetics, University of Veterinary Medicine, Bünteweg 17p, Hannover, 30559, Germany.
Wolfgang BaumgärtnerDepartment of Pathology, University of Veterinary Medicine, Bünteweg 17, Hannover, 30559, Germany.
Somporn TechangamsuwanDepartment of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand.
Martin LudlowResearch Center for Emerging Infections and Zoonoses, University of Veterinary Medicine (TiHo-RIZ), Bünteweg 17, Hannover, 30559, Germany.
Albert D M E OsterhausResearch Center for Emerging Infections and Zoonoses, University of Veterinary Medicine (TiHo-RIZ), Bünteweg 17, Hannover, 30559, Germany. albert.osterhaus@tiho-hannover.de.
University of Veterinary Medicine Hannover, Foundation · DEChulalongkorn University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine circoviruses (CanineCV's), belonging to the genus Circovirus of the Circoviridae family, were detected by next generation sequencing in samples from Thai dogs with respiratory symptoms. Genetic characterization and phylogenetic analysis of nearly complete CanineCV genomes suggested that natural recombination had occurred among different lineages of CanineCV's. Similarity plot and bootscaning analyses indicated that American and Chinese viruses had served as major and minor parental viruses, respectively. Positions of recombination breakpoints were estimated using maximum-likelihood frameworks with statistical significant testing. The putative recombination event was located in the Replicase gene, intersecting with open reading frame-3. Analysis of nucleotide changes confirmed the origin of the recombination event. This is the first description of naturally occurring recombinant CanineCV's that have resulted in the circulation of newly emerging CanineCV lineages.

Indexed as

AnimalsCircoviridae InfectionsCircovirusDog DiseasesDogsEvolution, MolecularGenome SizeGenome, ViralHigh-Throughput Nucleotide SequencingPhylogenyRecombination, GeneticRespiratory Tract DiseasesSequence Analysis, DNAThailand

Identifiers

PMID29760429
PMCPMC5951951
OpenAlexW2805674543

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.